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Gene Expression Data
Assay Details
Assay
Reference: J:171508 Ikegami D, et al., Sox9 sustains chondrocyte survival and hypertrophy in part through Pik3ca-Akt pathways. Development. 2011 Apr;138(8):1507-19
Assay type: RNA in situ
MGI Accession ID: MGI:7286332
Gene symbol: Col10a1
Gene name: collagen, type X, alpha 1
Probe: Col10a1 probe18
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1C Sox9flox/+: embryonic day 13.5; Sox9tm2Crm/Sox9+ (more )
Structure Cell Type Level Pattern Image Note
TS21: humerus cartilage condensation hypertrophic chondrocyte Present 1C Col10a1 Sox9flox/+
Specimen 1C 11Enh-Cre; Sox9flox/flox: embryonic day 13.5; Sox9tm2Crm/Sox9tm2Crm, Tg(Col11a2-cre)1Ntsu/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS21: humerus cartilage condensation hypertrophic chondrocyte Absent 1C Col10a1 11Enh-Cre; Sox9flox/flox
Specimen 1D Sox9flox/+: embryonic day 14.5; Sox9tm2Crm/Sox9+ (more )
Note: Proximal humerus.
Structure Cell Type Level Pattern Image Note
TS22: humerus cartilage condensation hypertrophic chondrocyte Present 1D Col10a1 Sox9flox/+
Specimen 1D 11Enh-Cre; Sox9flox/flox: embryonic day 14.5; Sox9tm2Crm/Sox9tm2Crm, Tg(Col11a2-cre)1Ntsu/0 (more )
Note: Conditional mutant. Proximal humerus.
Structure Cell Type Level Pattern Image Note
TS22: humerus cartilage condensation hypertrophic chondrocyte Absent 1D Col10a1 11Enh-Cre; Sox9flox/flox
Specimen 3A Sox9flox/+: embryonic day 13.5; Sox9tm2Crm/Sox9+ (more )
Note: Proximal humerus.
Structure Cell Type Level Pattern Image Note
TS21: humerus cartilage condensation hypertrophic chondrocyte Present Regionally restricted 3A Col10a1 Sox9flox/+ Expression was detected in the center of cartilage.
Specimen 3A 11Prom-Cre; Sox9flox/flox: embryonic day 13.5; Sox9tm2Crm/Sox9tm2Crm, Tg(Col11a2-cre)2Ntsu/0 (more )
Note: Conditional mutant. Proximal humerus.
Structure Cell Type Level Pattern Image Note
TS21: humerus cartilage condensation hypertrophic chondrocyte Absent 3A Col10a1 11Prom-Cre; Sox9flox/flox
Specimen 3D Sox9flox/+: embryonic day 14.5; Sox9tm2Crm/Sox9+ (more )
Structure Cell Type Level Pattern Image Note
TS22: humerus cartilage condensation hypertrophic chondrocyte Present Regionally restricted 3D Col10a1 Sox9flox/+ Expression was detected in the central region of humeral cartilage.
Specimen 3D 11Prom-Cre; Sox9flox/flox: embryonic day 14.5; Sox9tm2Crm/Sox9tm2Crm, Tg(Col11a2-cre)2Ntsu/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS22: humerus cartilage condensation hypertrophic chondrocyte Absent 3D Col10a1 11Prom-Cre; Sox9flox/flox
Specimen 5B Sox9flox/+; Ptenflox/+: embryonic day 14.5; Ptentm2Mak/Pten+, Sox9tm2Crm/Sox9+ (more )
Structure Level Pattern Image Note
TS22: humerus cartilage condensation Present 5B Col10a1 Sox9flox/+;Ptenflox/+
Specimen 5B 11Prom-Cre; Sox9flox/flox; Pten+/+: embryonic day 14.5; Sox9tm2Crm/Sox9tm2Crm, Tg(Col11a2-cre)2Ntsu/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: humerus cartilage condensation Absent 5B Col10a1 11Prom-Cre;Sox9flox/flox;Pten+/+
Specimen 5B 11Prom-Cre; Sox9flox/flox; Ptenflox/flox: embryonic day 14.5; Ptentm2Mak/Ptentm2Mak, Sox9tm2Crm/Sox9tm2Crm, Tg(Col11a2-cre)2Ntsu/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: humerus cartilage condensation Present Regionally restricted 5B Col10a1 11Prom-Cre;Sox9flox/flox;Ptenflox/flox Expression of Col10a1 was partially restored in the 11Prom-Cre; Sox9<flox/flox>; Pten<flox/flox> conditional mutant.
Specimen S2C Sox9flox/wt: embryonic day 15.5; Sox9tm2Crm/Sox9+ (more )
Note: Proximal humerus.
Structure Level Pattern Image Note
TS23: humerus Present S2C Col10a1 Sox9flox/+
Specimen S2C 11Enh-Cre; Sox9flox/flox: embryonic day 15.5; Sox9tm2Crm/Sox9tm2Crm, Tg(Col11a2-cre)1Ntsu/0 (more )
Note: Conditional mutant. Proximal humerus.
Structure Level Pattern Image Note
TS23: humerus Absent S2C Col10a1 11Enh-Cre;Sox9flox/flox
Specimen S4A Sox9flox/+: embryonic day 14.5; Sox9tm2Crm/Sox9+ (more )
Note: Proximal humerus.
Structure Level Pattern Image Note
TS22: humerus cartilage condensation Present S4A Col10a1 Sox9flox/+
Specimen S4A 11Prom-Cre; Sox9flox/flox: embryonic day 14.5; Sox9tm2Crm/Sox9tm2Crm, Tg(Col11a2-cre)2Ntsu/0 (more )
Note: Conditional mutant. Proximal humerus.
Structure Level Pattern Image Note
TS22: humerus cartilage condensation Absent S4A Col10a1 11Prom-Cre;Sox9flox/flox
Specimen S6 Sox9flox/+; Ptenflox/+: embryonic day 14.5; Ptentm2Mak/Pten+, Sox9tm2Crm/Sox9+ (more )
Structure Level Pattern Image Note
TS22: humerus cartilage condensation Present S6_Col10a1 Sox9flox/+;Ptenflox/+
Specimen S6 11Prom-Cre; Sox9flox/flox; Pten+/+: embryonic day 14.5; Sox9tm2Crm/Sox9tm2Crm, Tg(Col11a2-cre)2Ntsu/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: humerus cartilage condensation Absent S6_Col10a1 11Prom-Cre;Sox9flox/flox;Pten+/+
Specimen S6 11Prom-Cre; Sox9flox/flox; Ptenflox/flox: embryonic day 14.5; Ptentm2Mak/Ptentm2Mak, Sox9tm2Crm/Sox9tm2Crm, Tg(Col11a2-cre)2Ntsu/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: humerus cartilage condensation Present Regionally restricted S6_Col10a1 11Prom-Cre;Sox9flox/flox;Ptenflox/flox Expression of Col10a1 was partially restored in the 11Prom-Cre; Sox9<flox/flox>; Pten<flox/flox> conditional mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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