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Gene Expression Data
Assay Details
Assay
Reference: J:309496 Jiang C, et al., AATYK is a Novel Regulator of Oligodendrocyte Differentiation and Myelination. Neurosci Bull. 2018 Jun;34(3):527-533
Assay type: RNA in situ
MGI Accession ID: MGI:7281586
Gene symbol: Aatk
Gene name: apoptosis-associated tyrosine kinase
Probe: AATYK probe1
Probe preparation: labelled with digoxigenin RNA
Results
Specimen 1A: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: spinal cord Absent 1A No specific expression at E16.5
Specimen 1B: embryonic day 18.5 (more )
Structure Cell Type Level Pattern Image Note
TS26: spinal cord white matter oligodendrocyte Present 1B Expression started at E18.5 in spinal white matter.
Specimen 1C: postnatal day 4 (more )
Structure Cell Type Level Pattern Image Note
TS28: spinal cord oligodendrocyte Present 1C Expression progressively increased between E18.5 and P7.
Specimen 1D: postnatal day 7 (more )
Structure Cell Type Level Pattern Image Note
TS28: spinal cord oligodendrocyte Present 1D Expression progressively increased between E18.5 and P7.
Specimen 1E: postnatal day 15 (more )
Structure Cell Type Level Pattern Image Note
TS28: spinal cord oligodendrocyte Present Scattered 1E Expression scattered throughout cord at P15.
Specimen 1F: postnatal day 30 (more )
Structure Cell Type Level Pattern Image Note
TS28: spinal cord white matter oligodendrocyte Weak 1F Expression gradually decreased in white matter.
TS28: spinal cord gray matter neuron Present 1F Expression detectable in gray matter.
Specimen 1G: postnatal day 15 (more )
Note: Double labeled: blue - Aatk; brown - Olig2 (assay MGI:7281589).
Structure Level Pattern Image Note
TS28: corpus callosum Present 1G
Specimen 1H: postnatal day 3; Myrftm1Barr/Myrf+, Olig1tm1(cre)Rth/Olig1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: spinal cord white matter Present 1H
Specimen 1I: postnatal day 3; Myrftm1Barr/Myrftm1Barr, Olig1tm1(cre)Rth/Olig1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: spinal cord white matter Absent 1I Expressing cells in white matter were completely lost.
Specimen 2G: postnatal week 8-10 (more )
Structure Level Pattern Image Note
TS28: corpus callosum Present 2G
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory