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Gene Expression Data
Assay Details
Assay
Reference: J:181888 Ashe A, et al., Mutations in mouse Ift144 model the craniofacial, limb and rib defects in skeletal ciliopathies. Hum Mol Genet. 2012 Apr 15;21(8):1808-23
Assay type: RNA in situ
MGI Accession ID: MGI:7279187
Gene symbol: Dusp6
Gene name: dual specificity phosphatase 6
Probe: Dusp6 probe3
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 7I: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: forelimb bud Present 7I

Specimen 7J: embryonic day 10.5; Wdr19twto/Wdr19twto (more )
Structure Level Pattern Image Note
TS17: forelimb bud Present Regionally restricted 7J Expression shifted anteriorly. Much less obvious reduction in posterior expression.

Specimen 7K: embryonic day 10.5; Wdr19dmhd/Wdr19twto (more )
Structure Level Pattern Image Note
TS17: forelimb bud Weak Regionally restricted 7K Expression downregulated, with expression shifted anteriorly, reduced in posterior region.

Specimen 7L: embryonic day 10.5; Wdr19dmhd/Wdr19dmhd (more )
Structure Level Pattern Image Note
TS17: forelimb bud Weak Regionally restricted 7L Expression downregulated, with expression shifted anteriorly, reduced in posterior region.

Specimen S4I: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: hindlimb bud Present S4I

Specimen S4J: embryonic day 10.5; Wdr19twto/Wdr19twto (more )
Structure Level Pattern Image Note
TS17: hindlimb bud Present Regionally restricted S4J Expression shifted anteriorly. Expression similar in hindlimb of all 3 mutant genotypes.

Specimen S4K: embryonic day 10.5; Wdr19dmhd/Wdr19twto (more )
Structure Level Pattern Image Note
TS17: hindlimb bud Present Regionally restricted S4K Expression shifted anteriorly. Expression similar in hindlimb of all 3 mutant genotypes.

Specimen S4L: embryonic day 10.5; Wdr19dmhd/Wdr19dmhd (more )
Structure Level Pattern Image Note
TS17: hindlimb bud Present Regionally restricted S4L Expression shifted anteriorly. Expression similar in hindlimb of all 3 mutant genotypes.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory