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Gene Expression Data
Assay Details
Assay
Reference: J:181888 Ashe A, et al., Mutations in mouse Ift144 model the craniofacial, limb and rib defects in skeletal ciliopathies. Hum Mol Genet. 2012 Apr 15;21(8):1808-23
Assay type: RNA in situ
MGI Accession ID: MGI:7279185
Gene symbol: Shh
Gene name: sonic hedgehog
Probe: Shh probe212
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 7A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: forelimb bud Present Regionally restricted 7A Expression in posterior of limb.

Specimen 7B: embryonic day 10.5; Wdr19twto/Wdr19twto (more )
Structure Level Pattern Image Note
TS17: forelimb bud Present Regionally restricted 7B Expression unaltered relative to controls.

Specimen 7C: embryonic day 10.5; Wdr19dmhd/Wdr19twto (more )
Structure Level Pattern Image Note
TS17: forelimb bud Present Regionally restricted 7C Expression expanded anteriorly along distal periphery.

Specimen 7D: embryonic day 10.5; Wdr19dmhd/Wdr19dmhd (more )
Structure Level Pattern Image Note
TS17: forelimb bud Present Regionally restricted 7D Expression expanded anteriorly along distal periphery.

Specimen 7M: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: forelimb bud Present Regionally restricted 7M Expression in posterior of limb.

Specimen 7N: embryonic day 11.5; Wdr19twto/Wdr19twto (more )
Structure Level Pattern Image Note
TS19: forelimb bud Present Regionally restricted 7N Expression unaltered relative to controls.

Specimen 7O: embryonic day 11.5; Wdr19dmhd/Wdr19twto (more )
Structure Level Pattern Image Note
TS19: forelimb bud Present Regionally restricted 7O More discontinuous expanded domain of expression at E11.5.

Specimen S4A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: hindlimb bud Present Regionally restricted S4A Expression in posterior of limb.

Specimen S4B: embryonic day 10.5; Wdr19twto/Wdr19twto (more )
Structure Level Pattern Image Note
TS17: hindlimb bud Present Regionally restricted S4B Expression unaltered relative to controls.

Specimen S4C: embryonic day 10.5; Wdr19dmhd/Wdr19twto (more )
Structure Level Pattern Image Note
TS17: hindlimb bud Present Regionally restricted S4C Expression not expanded anteriorly in hindlimb bud at E10.5.

Specimen S4D: embryonic day 10.5; Wdr19dmhd/Wdr19dmhd (more )
Structure Level Pattern Image Note
TS17: hindlimb bud Present Regionally restricted S4D Expression not expanded anteriorly in hindlimb bud at E10.5.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/28/2024
MGI 6.13
The Jackson Laboratory