Tg(IFIH1*)#Hkato
Transgene Detail
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| Symbol: |
Tg(IFIH1*)#Hkato |
| Name: |
transgene instertion, Hiroki Kato |
| MGI ID: |
MGI:7278815 |
| Synonyms: |
MDA5 R779H Tg |
| Transgene: |
Tg(IFIH1*)#Hkato Location: unknown
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| Alliance: |
Tg(IFIH1*)#Hkato page
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| Transgene Type: |
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Transgenic (Humanized sequence, Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(IFIH1*)#Hkato expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| human |
IFIH1 (64135) |
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human gene with p.R779H mutation associated with Aicardi-Goutieres Syndrome (AGS). |
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Mutation details: The insertion comprises a BAC containing the human interferon induced with helicase C domain 1 gene with a p.R779H mutation (amino-acid 779 arginine to histidine) associated with Aicardi-Goutieres Syndrome (AGS).
(J:324284)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:324284 Ohto T, et al., Intracellular virus sensor MDA5 mutation develops autoimmune myocarditis and nephritis. J Autoimmun. 2022 Feb;127:102794 |
| All: |
1 reference(s) |
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Analysis Tools
