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Gene Expression Data
Assay Details
Assay
Reference: J:132315 Lynn FC, et al., MicroRNA expression is required for pancreatic islet cell genesis in the mouse. Diabetes. 2007 Dec;56(12):2938-45
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7266736
Gene symbol: Neurog3
Gene name: neurogenin 3
Antibody: anti-Neurogenin3
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 5C: embryonic day 15.5; Dicer1tm1Bdh/Dicer1+, Tg(Pdx1-cre)89.1Dam/0 (more )
Note: Conditional mutant. Double labeled: green - Neurog3; red - Pdx1 (assay MGI:7266724).
Structure Cell Type Level Pattern Image Note
TS23: pancreas progenitor cell of endocrine pancreas Present 5C Expression in committed endocrine progenitors.

Specimen 5D: embryonic day 15.5; Dicer1tm1Bdh/Dicer1tm1Bdh, Tg(Pdx1-cre)89.1Dam/0 (more )
Note: Conditional mutant. Double labeled: green - Neurog3; red - Pdx1 (assay MGI:7266724).
Structure Cell Type Level Pattern Image Note
TS23: pancreas progenitor cell of endocrine pancreas Trace 5D Dramatic (89%) reduction in expressing cells compared with control.

Specimen 5E: embryonic day 15.5; Dicer1tm1Bdh/Dicer1+, Tg(Pdx1-cre)89.1Dam/0 (more )
Note: Conditional mutant. Double labeled: green - Neurog3; red - Gcg (assay MGI:7266729).
Structure Cell Type Level Pattern Image Note
TS23: pancreas progenitor cell of endocrine pancreas Present 5E Expression in committed endocrine progenitors.

Specimen 5F: embryonic day 15.5; Dicer1tm1Bdh/Dicer1tm1Bdh, Tg(Pdx1-cre)89.1Dam/0 (more )
Note: Conditional mutant. Double labeled: green - Neurog3; red - Gcg (assay MGI:7266729).
Structure Cell Type Level Pattern Image Note
TS23: pancreas progenitor cell of endocrine pancreas Trace 5F Dramatic (89%) reduction in expressing cells compared with control.

Specimen 5G: embryonic day 15.5; Dicer1tm1Bdh/Dicer1+, Tg(Pdx1-cre)89.1Dam/0 (more )
Note: Conditional mutant. Double labeled: green - Neurog3; red - Muc1 (assay MGI:7266735).
Structure Cell Type Level Pattern Image Note
TS23: pancreas progenitor cell of endocrine pancreas Present 5G Expression in committed endocrine progenitors.

Specimen 5H: embryonic day 15.5; Dicer1tm1Bdh/Dicer1tm1Bdh, Tg(Pdx1-cre)89.1Dam/0 (more )
Note: Conditional mutant. Double labeled: green - Neurog3; red - Muc1 (assay MGI:7266735).
Structure Cell Type Level Pattern Image Note
TS23: pancreas progenitor cell of endocrine pancreas Trace 5H Dramatic (89%) reduction in expressing cells compared with control.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory