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Gene Expression Data
Assay Details
Assay
Reference: J:132315 Lynn FC, et al., MicroRNA expression is required for pancreatic islet cell genesis in the mouse. Diabetes. 2007 Dec;56(12):2938-45
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7266724
Gene symbol: Pdx1
Gene name: pancreatic and duodenal homeobox 1
Antibody: anti-Pdx1 polyclonal
Detection system: Secondary antibody coupled to Cy3
Results
Specimen 5C: embryonic day 15.5; Dicer1tm1Bdh/Dicer1+, Tg(Pdx1-cre)89.1Dam/0 (more )
Note: Conditional mutant. Double labeled: red - Pdx1; green - Neurog3 (assay MGI:7266736).
Structure Cell Type Level Pattern Image Note
TS23: endocrine pancreas type B pancreatic cell Strong 5C Strong expression in nascent beta-cells.
TS23: pancreatic duct Weak Regionally restricted 5C Weak expression in majority of cells lining ducts.
Specimen 5D: embryonic day 15.5; Dicer1tm1Bdh/Dicer1tm1Bdh, Tg(Pdx1-cre)89.1Dam/0 (more )
Note: Conditional mutant. Double labeled: red - Pdx1; green - Neurog3 (assay MGI:7266736).
Structure Cell Type Level Pattern Image Note
TS23: endocrine pancreas type B pancreatic cell Weak 5D Decreased number of strongly expressing cells compared with control.
TS23: pancreatic duct Weak 5D Ductal expression not grossly altered compared with control.
Specimen S1A/C: embryonic day 15.5; Dicer1tm1Bdh/Dicer1+, Tg(Pdx1-cre)89.1Dam/0 (more )
Note: Conditional mutant. Double labeled: red - Pdx1; green - Dicer1 (assay MGI:7266739).
Structure Level Pattern Image Note
TS23: pancreas Present S1A , S1C
Specimen S1D/F: embryonic day 15.5; Dicer1tm1Bdh/Dicer1tm1Bdh, Tg(Pdx1-cre)89.1Dam/0 (more )
Note: Conditional mutant. Double labeled: red - Pdx1; green - Dicer1 (assay MGI:7266739).
Structure Level Pattern Image Note
TS23: pancreas Present S1D , S1F
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory