Gene Expression Data
Assay Details
|
Assay
|
|
Reference:
|
J:318768
Carpentieri JA, et al., Endosomal trafficking defects alter neural progenitor proliferation and cause microcephaly. Nat Commun. 2022 Jan 10;13(1):16
|
|
Assay type:
|
Immunohistochemistry
|
|
MGI Accession ID:
|
MGI:7264461
|
|
Gene symbol:
|
Pax6
|
|
Gene name:
|
paired box 6
|
|
|
Results
|
Specimen
E12.5 WT not shown:
embryonic day 12.5
(more  )
Specimen
E12.5 WT not shown:
(close  )
|
Genetic Background:
|
involves: C57BL/6J
|
|
Age:
|
embryonic day 12.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
Specimen
E12.5 WDR81-/- not shown:
(close )
|
Genetic Background:
|
involves: C57BL/6J * DBA/2J
|
|
Mutant Allele(s):
|
Wdr81em1Curie/Wdr81em1Curie
|
|
Age:
|
embryonic day 12.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
Specimen
2a WT:
embryonic day 14.5
(more )
Note: Double labeled: blue - Pax6; red - phospho-Histone H3.
Specimen
2a WT:
(close )
|
Genetic Background:
|
involves: C57BL/6J
|
|
Age:
|
embryonic day 14.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Note:
|
Double labeled: blue - Pax6; red - phospho-Histone H3.
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS22: brain |
Present |
|
2a WT
|
Expression in radial glial progenitors.
|
Specimen
2a WDR81-/-:
embryonic day 14.5; Wdr81em1Curie/ Wdr81em1Curie
(more )
Note: Double labeled: blue - Pax6; red - phospho-Histone H3.
Specimen
2a WDR81-/-:
(close )
|
Genetic Background:
|
involves: C57BL/6J * DBA/2J
|
|
Mutant Allele(s):
|
Wdr81em1Curie/Wdr81em1Curie
|
|
Age:
|
embryonic day 14.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Note:
|
Double labeled: blue - Pax6; red - phospho-Histone H3.
|
Specimen
E16.5 WT not shown:
embryonic day 16.5
(more )
Specimen
E16.5 WT not shown:
(close )
|
Genetic Background:
|
involves: C57BL/6J
|
|
Age:
|
embryonic day 16.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
Specimen
E16.5 WDR81-/- not shown:
(close )
|
Genetic Background:
|
involves: C57BL/6J * DBA/2J
|
|
Mutant Allele(s):
|
Wdr81em1Curie/Wdr81em1Curie
|
|
Age:
|
embryonic day 16.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
Specimen
2c WT:
embryonic day 14.5
(more )
Specimen
2c WT:
(close )
|
Genetic Background:
|
involves: C57BL/6J
|
|
Age:
|
embryonic day 14.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
Specimen
2c WDR81-/-:
(close )
|
Genetic Background:
|
involves: C57BL/6J * DBA/2J
|
|
Mutant Allele(s):
|
Wdr81em1Curie/Wdr81em1Curie
|
|
Age:
|
embryonic day 14.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
Specimen
2e WT:
embryonic day 14.5
(more )
Specimen
2e WT:
(close )
|
Genetic Background:
|
involves: C57BL/6J
|
|
Age:
|
embryonic day 14.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
Specimen
2e WDR81-/-:
(close )
|
Genetic Background:
|
involves: C57BL/6J * DBA/2J
|
|
Mutant Allele(s):
|
Wdr81em1Curie/Wdr81em1Curie
|
|
Age:
|
embryonic day 14.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
Specimen
2g PAX6 WT:
embryonic day 14.5
(more )
Specimen
2g PAX6 WT:
(close )
|
Genetic Background:
|
involves: C57BL/6J
|
|
Age:
|
embryonic day 14.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS22: brain |
Present |
|
2g PAX6 WT
|
Expression in radial glial progenitors.
|
Specimen
2g PAX6 WDR81-/-:
(close )
|
Genetic Background:
|
involves: C57BL/6J * DBA/2J
|
|
Mutant Allele(s):
|
Wdr81em1Curie/Wdr81em1Curie
|
|
Age:
|
embryonic day 14.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Analysis Tools