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Gene Expression Data
Assay Details
Assay
Reference: J:318768 Carpentieri JA, et al., Endosomal trafficking defects alter neural progenitor proliferation and cause microcephaly. Nat Commun. 2022 Jan 10;13(1):16
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7264461
Gene symbol: Pax6
Gene name: paired box 6
Antibody: anti-Pax6 (#PRB-278P; #30130, #901301)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen E12.5 WT not shown: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: brain Present
Specimen E12.5 WDR81-/- not shown: embryonic day 12.5; Wdr81em1Curie/Wdr81em1Curie (more )
Structure Level Pattern Image Note
TS20: brain Present
Specimen 2a WT: embryonic day 14.5 (more )
Note: Double labeled: blue - Pax6; red - phospho-Histone H3.
Structure Level Pattern Image Note
TS22: brain Present 2a WT Expression in radial glial progenitors.
Specimen 2a WDR81-/-: embryonic day 14.5; Wdr81em1Curie/Wdr81em1Curie (more )
Note: Double labeled: blue - Pax6; red - phospho-Histone H3.
Structure Level Pattern Image Note
TS22: brain Present 2a WDR81-/- Expression in radial glial progenitors.
Specimen E16.5 WT not shown: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: brain Present
Specimen E16.5 WDR81-/- not shown: embryonic day 16.5; Wdr81em1Curie/Wdr81em1Curie (more )
Structure Level Pattern Image Note
TS24: brain Present
Specimen 2c WT: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: brain Present 2c WT (left) Expression in radial glial progenitors.
Specimen 2c WDR81-/-: embryonic day 14.5; Wdr81em1Curie/Wdr81em1Curie (more )
Structure Level Pattern Image Note
TS22: brain Present 2c WDR81-/- (left) Expression in radial glial progenitors.
Specimen 2e WT: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: brain Present 2e WT (left) Expression in radial glial progenitors.
Specimen 2e WDR81-/-: embryonic day 14.5; Wdr81em1Curie/Wdr81em1Curie (more )
Structure Level Pattern Image Note
TS22: brain Present 2e WDR81-/- (left) Expression in radial glial progenitors.
Specimen 2g PAX6 WT: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: brain Present 2g PAX6 WT Expression in radial glial progenitors.
Specimen 2g PAX6 WDR81-/-: embryonic day 14.5; Wdr81em1Curie/Wdr81em1Curie (more )
Structure Level Pattern Image Note
TS22: brain Present 2g PAX6 WDR81-/- No decrease in proportion of progenitors.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory