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Gene Expression Data
Assay Details
Assay
Reference: J:318768 Carpentieri JA, et al., Endosomal trafficking defects alter neural progenitor proliferation and cause microcephaly. Nat Commun. 2022 Jan 10;13(1):16
Assay type: RT-PCR
MGI Accession ID: MGI:7264455
Gene symbol: Wdr81
Gene name: WD repeat domain 81
Probe: Wdr81-pA, Wdr81-pB
Assay notes: Quantitative RT-PCR. Relative expression was normalized to p62. Primers specific for isoform 1.
Results
Image: 1b ISO1 ©

 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified Amount Genetic BackgroundMutant Allele(s)Sex
WT ISO1 E14.5 TS22: cerebral cortex Present (a) Not Specified; total RNA involves: C57BL/6J Not Specified
WT ISO2 Other lane(s) in blot use different probe(s)
WDR81 KO1 ISO1 E14.5 TS22: cerebral cortex Weak (b) Not Specified; total RNA involves: C57BL/6J * DBA/2J Wdr81em1Curie/Wdr81em1CurieNot Specified
WDR81 KO1 ISO2 Other lane(s) in blot use different probe(s)
Notes:
(a) Isoform 1 is highly dominant.
(b) Levels of isoform 1 strongly reduced compared to wildtype.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory