About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:316935 Chen Z, et al., DPPA2 and DPPA4 are dispensable for mouse zygotic genome activation and pre-implantation development. Development. 2021 Dec 15;148(24):dev200178
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7261223
Gene symbol: Dppa2
Gene name: developmental pluripotency associated 2
Results
Specimen 1B GV oocyte: postnatal adult (more )
Structure Level Pattern Image Note
TS28: primary oocyte Absent 1B Dppa2 GV oocyte
Specimen 1B 1-cell: embryonic day 0.5 (more )
Structure Level Pattern Image Note
TS1: 1-cell stage embryo Absent 1B Dppa2 1-cell
Specimen 1B Late 2-cell: embryonic day 1.0 (more )
Structure Level Pattern Image Note
TS2: 2-cell stage embryo Weak 1B Dppa2 late 2-cell
Specimen 1B 4-cell: embryonic day 2.0 (more )
Structure Level Pattern Image Note
TS3: 4-cell stage embryo Present 1B Dppa2 4-cell
Specimen 1B 8-cell: embryonic day 2.5 (more )
Structure Level Pattern Image Note
TS3: 8-cell stage embryo Present 1B Dppa2 8-cell
Specimen 1B Morula: embryonic day 3.0 (more )
Structure Level Pattern Image Note
TS3: compacted morula Present 1B Dppa2 Morula
Specimen 1B Mid blastocyst: embryonic day 3.5 (more )
Structure Level Pattern Image Note
TS4: blastocyst Present 1B Dppa2 Mid blastocyst
Specimen 1B Late blastocyst: embryonic day 4.0 (more )
Structure Level Pattern Image Note
TS5: blastocyst Present 1B Dppa2 Late blastocyst
Specimen 1D left: embryonic day 3.5 (more )
Structure Level Pattern Image Note
TS4: inner cell mass Present 1D Dppa2 left
Specimen 1D right: embryonic day 3.5 (more )
Structure Level Pattern Image Note
TS4: inner cell mass Present 1D Dppa2 right
Specimen 2C m-z+Dppa2: embryonic day 2.0; Dppa2em1Yzhg/Dppa2+, Tg(Gdf9-icre)5092Coo/0 (more )
Note: Conditional mutant. maternal KO
Structure Level Pattern Image Note
TS3: 4-cell stage embryo Present 2C DPPA2 m-z+Dppa2 Dppa2 signal intensity in maternal KO 4-cell embryos was largely comparable to that of wild type embryos.
Specimen 2C m-z-Dppa2: embryonic day 2.0; Dppa2em1Yzhg/Dppa2em1Yzhg, Tg(Gdf9-icre)5092Coo/0 (more )
Note: Conditional mutant. maternal-zygotic KO
Structure Level Pattern Image Note
TS3: 4-cell stage embryo Absent 2C DPPA2 m-z-Dppa2
Specimen 2C m-Z+Dppa4: embryonic day 2.0; Dppa4tm1.2Yam/Dppa4+, Tg(Gdf9-icre)5092Coo/0 (more )
Note: Conditional mutant. maternal KO
Structure Level Pattern Image Note
TS3: 4-cell stage embryo Present 2C DPPA2 m-z+Dppa4
Specimen 2C m-z-Dppa4: embryonic day 2.0; Dppa4tm1.2Yam/Dppa4tm1.2Yam, Tg(Gdf9-icre)5092Coo/0 (more )
Note: Conditional mutant. maternal-zygotic KO
Structure Level Pattern Image Note
TS3: 4-cell stage embryo Trace 2C DPPA2 m-z-Dppa4 The Dppa2 signal was reduced in the Dppa4-maternal-zygotic KO.
Specimen 3D m-z+Dppa2: embryonic day 3.5; Dppa2em1Yzhg/Dppa2+, Tg(Gdf9-icre)5092Coo/0 (more )
Note: Conditional mutant. maternal KO
Structure Level Pattern Image Note
TS4: inner cell mass Present 3D DPPA2 m-z+Dppa2
Specimen 3D m-z-Dppa2: embryonic day 3.5; Dppa2em1Yzhg/Dppa2em1Yzhg, Tg(Gdf9-icre)5092Coo/0 (more )
Note: Conditional mutant. maternal-zygotic KO
Structure Level Pattern Image Note
TS4: inner cell mass Absent 3D DPPA2 m-z-Dppa2
Specimen 3D m-Z+Dppa4: embryonic day 3.5; Dppa4tm1.2Yam/Dppa4+, Tg(Gdf9-icre)5092Coo/0 (more )
Note: Conditional mutant. maternal KO
Structure Level Pattern Image Note
TS4: inner cell mass Present 3D DPPA2 m-z+Dppa4
Specimen 3D m-z-Dppa4: embryonic day 3.5; Dppa4tm1.2Yam/Dppa4tm1.2Yam, Tg(Gdf9-icre)5092Coo/0 (more )
Note: Conditional mutant. maternal-zygotic KO
Structure Level Pattern Image Note
TS4: inner cell mass Trace 3D DPPA2 m-z-Dppa4
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory