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Gene Expression Data
Assay Details
Assay
Reference: J:110714 Barrionuevo F, et al., Sox9 is required for notochord maintenance in mice. Dev Biol. 2006 Jul 1;295(1):128-40
Assay type: RNA in situ
MGI Accession ID: MGI:7258383
Gene symbol: Acan
Gene name: aggrecan
Probe: Agc1 probe2
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 5I: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: notochord Present 5I
TS19: sclerotome Present Regionally restricted 5I Expression in presumtpive verterbral regions of perinotochordal area
Specimen 5J: embryonic day 11.5; Sox9tm1Gsr/Sox9tm1Gsr, Krt19tm1(cre)Mmt/Krt19+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: notochord Present 5J Expression persisted, restricted to remaining notochord cells.
TS19: sclerotome Absent 5J
Specimen 6H: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: notochord Strong 6H
TS21: sclerotome Strong Regionally restricted 6H Highly expressed in vertebral regions,
Specimen 6L: embryonic day 13.5; Sox9tm1Gsr/Sox9tm1Gsr, Krt19tm1(cre)Mmt/Krt19+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: notochord Present 6L Expression in remaining notochord cells.
TS21: vertebral cartilage condensation Present 6L Expression in cartilage cores.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory