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Gene Expression Data
Assay Details
Assay
Reference: J:218166 Zhulyn O, et al., Ptch2 shares overlapping functions with Ptch1 in Smo regulation and limb development. Dev Biol. 2015 Jan 15;397(2):191-202
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:7256486
Gene symbol: Ptch2
Gene name: patched 2
Reporter: lacZ
Direct Detection
Results
Specimen 3B: embryonic day 11.0; Ptch2tm1Bjw/Ptch2+ (more )
Structure Level Pattern Image Note
TS18: forelimb bud mesenchyme Present Regionally restricted 3B Expression in posterior mesenchyme.
Specimen 3B': embryonic day 11.0; Ptch2tm1Bjw/Ptch2+ (more )
Structure Level Pattern Image Note
TS18: forelimb bud apical ectodermal ridge Present Regionally restricted 3B' Authors report expression in posterior apical ectodermal ridge.
Specimen 3D: embryonic day 12.5; Ptch2tm1Bjw/Ptch2+ (more )
Structure Level Pattern Image Note
TS20: hand mesenchyme Present Regionally restricted 3D Expression in posterior mesenchyme.
Specimen 3D': embryonic day 12.5; Ptch2tm1Bjw/Ptch2+ (more )
Structure Level Pattern Image Note
TS20: hand epithelium Present Regionally restricted 3D' Authors report expression in posterior apical ectodermal ridge.
Specimen 3F: embryonic day 14.5; Ptch2tm1Bjw/Ptch2+ (more )
Structure Level Pattern Image Note
TS22: hand Present 3F
Specimen S4B: embryonic day 12.5; Ptch2tm1Bjw/Ptch2+ (more )
Structure Level Pattern Image Note
TS20: limb mesenchyme Present Regionally restricted S4B Expression in posterior mesenchyme.
TS20: limb epithelium Present S4B Expression in ectoderm of limb.
TS20: vibrissa Present S4B
TS20: brain Present S4B
TS20: spinal cord Present S4B
Specimen S4C: embryonic day 12.5; Ptch2tm1Bjw/Ptch2tm1Bjw (more )
Structure Level Pattern Image Note
TS20: limb mesenchyme Present Regionally restricted S4C Expression in posterior mesenchyme.
TS20: limb epithelium Present S4C Expression in ectoderm of limb.
TS20: vibrissa Present S4C
TS20: brain Present S4C
TS20: spinal cord Present S4C
Specimen S5C: embryonic day 11.5; Ptch2tm1Bjw/Ptch2+ (more )
Structure Level Pattern Image Note
TS19: apical ectodermal ridge Present Regionally restricted S5C No expression in anterior apical ectodermal ridge (AER).
Specimen S5C': embryonic day 12.5; Ptch2tm1Bjw/Ptch2+ (more )
Structure Level Pattern Image Note
TS20: limb epithelium Present Regionally restricted S5C' No expression in the anterior apical ectodermal ridge (AER).
Specimen S5D: embryonic day 11.5; Ptch1tm1Bjw/Ptch1tm1Mps, Ptch2tm1Bjw/Ptch2+, Tg(Msx2-cre)5Rem/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: apical ectodermal ridge Present Regionally restricted S5D Ectopic expression in anterior apical ectodermal ridge (AER).
Specimen S5D': embryonic day 12.5; Ptch1tm1Bjw/Ptch1tm1Mps, Ptch2tm1Bjw/Ptch2+, Tg(Msx2-cre)5Rem/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: limb epithelium Present Regionally restricted S5D' Ectopic expression in anterior apical ectodermal ridge (AER).
Specimen 5M: embryonic day 12.5; Ptch2tm1Bjw/Ptch2+ (more )
Structure Level Pattern Image Note
TS20: limb epithelium Present Regionally restricted 5M No expression in anterior apical ectodermal ridge (AER).
Specimen 5M': embryonic day 12.5; Ptch1tm1Bjw/Ptch1tm1Mps, Ptch2tm1Bjw/Ptch2+, Tg(Msx2-cre)5Rem/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: limb epithelium Present Regionally restricted 5M' Ectopic expression in anterior apical ectodermal ridge (AER).
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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