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Gene Expression Data
Assay Details
Assay
Reference: J:255172 Droscha CJ, et al., Osteoblast-specific deletion of Hrpt2/Cdc73 results in high bone mass and increased bone turnover. Bone. 2017 May;98:68-78
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6885869
Gene symbol: Casp3
Gene name: caspase 3
Antibody: anti-cleaved Caspase-3
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Assay notes: The antibody used recognizes the cleaved form of the protein.
Results
Specimen 1G: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: embryo Absent 1G

Specimen 1H: embryonic day 11.5; Cdc73tm1Btt/Cdc73tm1Btt, Twist2tm1(cre)Dor/Twist2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: embryo Present 1H There is widespread apoptosis within the developing mesenchyme.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/24/2026
MGI 6.24
The Jackson Laboratory