Hmcn2 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:310857 Welcker D, et al., Hemicentin-1 is an essential extracellular matrix component of the dermal-epidermal and myotendinous junctions. Sci Rep. 2021 Sep 9;11(1):17926
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:6883741
Gene symbol:	Hmcn2
Gene name:	hemicentin 2

Antibody:	anti-Hmcn2
Detection system:	Secondary antibody coupled to Alexa Fluor 488

Results

1K ©

Specimen 1K: embryonic day 1.5 (more

)

Structure	Level	Pattern	Image	Note
TS2: 2-cell stage embryo	Ambiguous		1K	No expression in the cleavage furrow.

1N ©

Specimen 1N: embryonic day 14.5 (more

)

Structure	Level	Pattern	Image	Note
TS22: epidermis	Present	Regionally restricted	1N	Expressed in the pericellular space of basal keratinocytes.

S2_1A ©

S2_1A" ©

S2_1A' ©

Specimen S2_1A/A'/A": postnatal day 1 (more

)
Note: Double labeled: green - Hmcn2; red - Hmcn1 (assay MGI:6883742).

Structure	Level	Pattern	Image	Note
TS27: epidermis	Present		S2_1A , S2_1A'	Expressed in the pericellular space of basal keratinocytes.
TS27: lower leg muscle	Present		S2_1A , S2_1A"	Expressed in the endomysium of myofibers, with strong enrichment at the sites where myofibers were in close proximity to the tendon.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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