Lrp2 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:315320 Moore R, et al., The primitive endoderm segregates from the epiblast in beta1 integrin-deficient early mouse embryos. Mol Cell Biol. 2014 Feb;34(3):560-72
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:6871028
Gene symbol:	Lrp2
Gene name:	low density lipoprotein receptor-related protein 2

Antibody:	anti-megalin (P-20; sc-16478)
Detection system:	Secondary antibody coupled to Alexa Fluor

Results

Specimen 6A (middle): embryonic day 5.5; Itgb1^tm1Efu/Itgb1^tm1.1Efu (more

)
Note: Double labeled: red - Lrp2; green - Cdh1 (assay MGI:6871027).

Structure	Level	Pattern	Image	Note
TS7: primitive endoderm	Present		6A (middle)

Specimen 6B (right): embryonic day 5.5; Itgb1^tm1Efu/Itgb1^tm1.1Efu, Tg(Ttr-cre)1Hadj/0 (more

)
Note: Conditional mutant. Double labeled: red - Lrp2; green - Cdh1 (assay MGI:6871027).

Structure	Level	Pattern	Image	Note
TS7: primitive endoderm	Present		6B (right)	Authors report visceral endoderm appeared intact and polarized.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 03/25/2025 MGI 6.24