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Gene Expression Data
Assay Details
Assay
Reference: J:315320 Moore R, et al., The primitive endoderm segregates from the epiblast in beta1 integrin-deficient early mouse embryos. Mol Cell Biol. 2014 Feb;34(3):560-72
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6871028
Gene symbol: Lrp2
Gene name: low density lipoprotein receptor-related protein 2
Antibody: anti-megalin (P-20; sc-16478)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 6A (middle): embryonic day 5.5; Itgb1tm1Efu/Itgb1tm1.1Efu (more )
Note: Double labeled: red - Lrp2; green - Cdh1 (assay MGI:6871027).
Structure Level Pattern Image Note
TS7: primitive endoderm Present 6A (middle)
Specimen 6B (right): embryonic day 5.5; Itgb1tm1Efu/Itgb1tm1.1Efu, Tg(Ttr-cre)1Hadj/0 (more )
Note: Conditional mutant. Double labeled: red - Lrp2; green - Cdh1 (assay MGI:6871027).
Structure Level Pattern Image Note
TS7: primitive endoderm Present 6B (right) Authors report visceral endoderm appeared intact and polarized.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory