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Gene Expression Data
Assay Details
Assay
Reference: J:307192 Yadav PS, et al., Stat3 loss in mesenchymal progenitors causes Job syndrome-like skeletal defects by reducing Wnt/beta-catenin signaling. Proc Natl Acad Sci U S A. 2021 Jun 29;118(26):e2020100118
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6831024
Gene symbol: Stat3
Gene name: signal transducer and activator of transcription 3
Antibody: anti-Phospho-Stat3-Y705 (AP0070)
Detection system: Secondary antibody coupled to Alexa Fluor 568
Results
Specimen S1A Prrx1Cre;Stat3C/+: postnatal day 0; Stat3tm1Flv/Stat3+, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: humerus Present Regionally restricted S1A Prrx1Cre;Stat3C/+ Expression is in the differentiating osteoblasts and bone marrow.
TS27: bone marrow Present S1A Prrx1Cre;Stat3C/+
Specimen S1A Prrx1Cre;Stat3C/C: postnatal day 0; Stat3tm1Flv/Stat3tm1Flv, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: bone marrow Present Single cells S1A Prrx1Cre;Stat3C/C
TS27: humerus Present Single cells S1A Prrx1Cre;Stat3C/C
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory