Gene Expression Data
Assay Details
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Assay
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Reference:
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J:138140
Aqeilan RI, et al., The WWOX tumor suppressor is essential for postnatal survival and normal bone metabolism. J Biol Chem. 2008 Aug 1;283(31):21629-39
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Assay type:
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In situ reporter (knock in)
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MGI Accession ID:
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MGI:6825747
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Gene symbol:
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Wwox
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Gene name:
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WW domain-containing oxidoreductase
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Reporter:
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lacZ
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Direct Detection
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Results
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Specimen
2B:
(close  )
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Genetic Background:
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involves: 129X1/SvJ * C57BL/6J
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Mutant Allele(s):
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Wwoxtm1Ria/Wwoxtm1Ria
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Age:
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embryonic day 17.5
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Sex:
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Not Specified
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Type:
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section from whole mount
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS25: forelimb tendon |
Present |
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2B
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| TS25: femur |
Present |
Regionally restricted |
2Bb
,
2Bd
,
2Ba
,
2B
,
2Bc
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Expression is in chondrocytes, osteoblasts on the endosteal surface, and osteoblasts forming bone in the periosteal side of the limb.
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| TS25: forelimb musculature |
Absent |
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2Bd
,
2B
,
2Ba
,
2Bb
,
2Bc
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Specimen
2C:
(close )
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Genetic Background:
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involves: 129X1/SvJ * C57BL/6J
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Mutant Allele(s):
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Wwoxtm1Ria/Wwoxtm1Ria
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Age:
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embryonic day 17.5
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Sex:
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Not Specified
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Type:
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section from whole mount
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS25: vertebra |
Present |
Regionally restricted |
2D
,
2C
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Expression is in chondrocytes and osteoblasts.
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Specimen
2E:
(close )
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Genetic Background:
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involves: 129X1/SvJ * C57BL/6J
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Mutant Allele(s):
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Wwoxtm1Ria/Wwoxtm1Ria
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Age:
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embryonic day 17.5
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Sex:
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Not Specified
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Type:
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section from whole mount
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS25: chondrocranium |
Present |
Regionally restricted |
2E top
,
2E bottom
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Expression is in cells on the bone forming surfaces but not in mature osteocytes in the bone center.
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Analysis Tools
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