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Gene Expression Data
Assay Details
Assay
Reference: J:157895 Snippert HJ, et al., Lgr6 marks stem cells in the hair follicle that generate all cell lineages of the skin. Science. 2010 Mar 12;327(5971):1385-9
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6818653
Gene symbol: Lgr6
Gene name: leucine-rich repeat-containing G protein-coupled receptor 6
Reporter: GFP
Direct Detection
Results
Specimen 1G: postnatal day 20; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: First telogen stage. Double labeled: green - Lgr6 reporter; red - Cd34 (assay MGI:6822348).
Structure Level Pattern Image Note
TS28: hair follicle isthmus Present Regionally restricted 1G Expression is restricted to a limited number of cells at the central isthmus.
Specimen 1H: postnatal day 20; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: First telogen stage. Double labeled: green - Lgr6 reporter; red - Plet1 (assay MGI:6822349).
Structure Level Pattern Image Note
TS28: hair follicle isthmus Present Regionally restricted 1H Expression is restricted to a limited number of cells at the central isthmus.
Specimen 1I: postnatal day 20; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: First telogen stage. Double labeled: green - Lgr6 reporter; red - Lrig1 (assay MGI:6822350).
Structure Level Pattern Image Note
TS28: hair follicle isthmus Present Regionally restricted 1I Expression is restricted to a limited number of cells at the central isthmus.
Specimen S2B: embryonic day 17.5; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Structure Level Pattern Image Note
TS25: hair follicle Present S2B
Specimen S2C: embryonic day 17.5; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Structure Level Pattern Image Note
TS25: hair peg Present S2C
Specimen S2D: postnatal day 4; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Double labeled: green - Lgr6; red - Krt1 (assay MGI:6822359).
Structure Level Pattern Image Note
TS28: hair follicle isthmus Present S2D
TS28: epidermis Present Regionally restricted S2D Expression is seen in the interfollicular epidermis.
Specimen S2E: postnatal day 15; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: The red signal is autofluorescence.
Structure Level Pattern Image Note
TS28: hair follicle isthmus Present Regionally restricted S2E Expression is restricted to the top of the bulge.
Specimen S2F: postnatal day 20; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: First telogen stage. Double labeled: green - Lgr6; red - Krt1 (assay MGI:6822359).
Structure Level Pattern Image Note
TS28: hair follicle isthmus Present Regionally restricted S2F Expression is located on top of the bulge, at the central isthmus.
Specimen S2G: postnatal day 20; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: First telogen stage. Double labeled: green - Lgr6; red - Itga6 (assay MGI:6822360).
Structure Level Pattern Image Note
TS28: hair follicle isthmus Present Regionally restricted S2G Expression is located on top of the bulge, at the central isthmus.
Specimen S2H: postnatal day 37; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: The red signal is autofluorescence.
Structure Level Pattern Image Note
TS28: hair follicle isthmus Present Regionally restricted S2H Expression is seen in the central isthmus.
Specimen S2I: postnatal day 56; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: The red signal is autofluorescence.
Structure Level Pattern Image Note
TS28: hair follicle isthmus Present Regionally restricted S2I Expression is seen in the central isthmus.
Specimen S5A: embryonic day 17.5; Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Structure Level Pattern Image Note
TS25: hair peg Present S5A
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory