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Gene Expression Data
Assay Details
Assay
Reference: J:50592 Liu X, et al., Domain-specific gene disruption reveals critical regulation of neuregulin signaling by its cytoplasmic tail. Proc Natl Acad Sci U S A. 1998 Oct 27;95(22):13024-9
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6814702
Gene symbol: Nefm
Gene name: neurofilament, medium polypeptide
Antibody: anti-160kDa neurofilament
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 4a wt: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: acoustic ganglion Present 4a wt
TS17: facial ganglion Present 4a wt
TS17: glossopharyngeal ganglion Present 4a wt
TS17: trigeminal ganglion Present 4a wt
TS17: vagus ganglion Present 4a wt
Specimen 4a ko: embryonic day 10.5; Nrg1tm1Zhou/Nrg1tm1Zhou (more )
Structure Level Pattern Image Note
TS17: trigeminal ganglion Present Regionally restricted 4a ko The dorsal part, derived from neural-crest cells, its mandibular branch, and its projections toward the brain stem were absent.
TS17: vagus ganglion Present 4a ko The petrose and nodose ganglia were also reduced in size and their projections were hypoplastic and disorganized.
TS17: acoustic ganglion Present 4a ko
TS17: facial ganglion Present 4a ko
TS17: glossopharyngeal ganglion Present 4a ko
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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