Gp2 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:306246 He M, et al., Chloride channels regulate differentiation and barrier functions of the mammalian airway. Elife. 2020 Apr 14;9:e53085
Assay type:	RNA in situ
MGI Accession ID:	MGI:6781971
Gene symbol:	Gp2
Gene name:	glycoprotein 2 zymogen granule membrane

Results

4B Gp2/Foxj1 ©

4B merge ©

Specimen 4B: postnatal day 3 (more

)
Note: Triple labeled: teal - Gp2; magenta - Foxj1 (assay MGI:6781966); orange - Prr18 (assay MGI:6781972).

Structure	Level	Pattern	Image	Note
TS27: trachea epithelium	Present	Regionally restricted	4B Gp2/Foxj1 , 4B merge	Although this is considered a secretory cell marker, expression is also seen in "hybrid" cells that express ciliated cell markers.

Specimen 4 S1A wt lower: postnatal newborn (more

)
Note: Double labeled: green - Gp2; red - Foxj1 (assay MGI:6781966).

Structure	Level	Pattern	Image	Note
TS27: trachea epithelium	Present	Regionally restricted	4 S1A lower left	Expression is seen in secretory cells and in "hybrid" cells that express both secretory and ciliated cell markers.

Specimen 4 S1A Pofut^-/- lower: postnatal newborn; Pofut1^tm1Pst/Pofut1^tm1Pst (more

)
Note: Double labeled: green - Gp2; red - Foxj1 (assay MGI:6781966).

Structure	Level	Pattern	Image	Note
TS27: trachea epithelium	Present	Regionally restricted	4 S1A lower right	These mutants lack secretory cells (and, therefore, lack expression in them). Expression is retained in "hybrid" cells that express both secretory and ciliated cell markers.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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