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Gene Expression Data
Assay Details
Assay
Reference: J:281028 Kiyama T, et al., Essential Roles of Tbr1 in the Formation and Maintenance of the Orientation-Selective J-RGCs and a Group of OFF-Sustained RGCs in Mouse. Cell Rep. 2019 Apr 16;27(3):900-915.e5
Assay type: RNA in situ
MGI Accession ID: MGI:6781940
Gene symbol: Jam2
Gene name: junction adhesion molecule 2
Probe: Mm-Jam2 (467321)
Probe preparation: Antisense
Visualized with: Chromogenic
Assay notes: RNAscope assay. A C1 probe was used.
Results
Specimen 6C: postnatal day 7 (more )
Note: wild type
Structure Level Pattern Image Note
TS28: retina ganglion cell layer Present Single cells 6C , 6C' Expression is seen sporadically.
TS28: retina inner nuclear layer Present Non-Uniform 6C , 6C' Expression is seen sporadically in the lower half and more densely in the upper half.
TS28: retina outer nuclear layer Present Widespread 6C , 6C'
Specimen 6D: postnatal day 7; Tbr1tm2.1(Myc)Maoc/Tbr1tm2.1(Myc)Maoc, Tg(Six3-cre)69Frty/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: retina ganglion cell layer Present Single cells 6D , 6D' The number of expressing cells is significantly reduced in the mutant.
TS28: retina inner nuclear layer Present Non-Uniform 6D , 6D' As in wild type, expression is seen sporadically in the lower half and more densely in the upper half.
TS28: retina outer nuclear layer Present Widespread 6D' , 6D Expression is as seen in wild type.
Specimen S5A: postnatal day 21 (more )
Note: wild type
Structure Level Pattern Image Note
TS28: retina ganglion cell layer Present Single cells S5A
Specimen S5B: postnatal day 21; Tbr1tm2.1(Myc)Maoc/Tbr1tm2.1(Myc)Maoc, Tg(Six3-cre)69Frty/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: retina ganglion cell layer Present Single cells S5B Expression is reduced in the mutant compared to the control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory