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Gene Expression Data
Assay Details
Assay
Reference: J:309563 Rafipay A, et al., Knockdown of slit signaling during limb development leads to a reduction in humerus length. Dev Dyn. 2021 Sep;250(9):1340-1357
Assay type: RNA in situ
MGI Accession ID: MGI:6780203
Gene symbol: Robo1
Gene name: roundabout guidance receptor 1
Probe: Robo1 probe5
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1D: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: hand pre-cartilage condensation Present 1D
TS21: hand joint primordium Present Regionally restricted 1D Expression in metacarpophalangeal joints. Low level of expression in proximal interphalangeal point.
Specimen 1D': embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: foot pre-cartilage condensation Present 1D'
TS21: foot joint primordium Present Regionally restricted 1D' Expression in metatarsophalangeal joints. No expression in proximal interphalangeal point in hindlimb.
Specimen 1J: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: hand Present Regionally restricted 1J
TS22: forelimb interphalangeal joint Present Regionally restricted 1J Expression in proximal and distal interphalangeal joints.
Specimen 1J': embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: foot Present Regionally restricted 1J' Expression in foot plate.
TS22: hindlimb interphalangeal joint Present Regionally restricted 1J' Expression in proximal and distal interphalangeal joints.
Specimen 1P: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: forelimb interphalangeal joint Present 1P
TS23: metacarpal-phalangeal joint Present 1P
Specimen 1P': embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: hindlimb interphalangeal joint Present 1P'
TS23: metatarsal-phalangeal joint Present 1P'
Specimen 1V: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: hand mesenchyme Present Regionally restricted 1V Expression around periphery of interphalangeal joint.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory