Igs2em9(Ctsk-icre)Gpt
Endonuclease-mediated Allele Detail
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Symbol: |
Igs2em9(Ctsk-icre)Gpt |
Name: |
intergenic site 2; endonuclease-mediated mutation 9, GemPharmatech Co., Ltd |
MGI ID: |
MGI:6765437 |
Synonyms: |
CtskCre, H11em1Cin(Ctsk-iCre-polyA) |
Gene: |
Igs2 Location: unknown Genetic Position: Chr11, Syntenic
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Alliance: |
Igs2em9(Ctsk-icre)Gpt page
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Allele Type: |
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Endonuclease-mediated (Recombinase) |
Mutation: |
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Insertion
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Igs2em9(Ctsk-icre)Gpt expression driven by
1 gene
Knock-in expression driven by:
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Mutation details: CRISPR-targeting introduced the mouse promoter driving osteoclast-specific expression of the improved cre recombinase gene.
(J:310893)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Ctsk
(mouse)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Igs2 Mutation: |
68 strains or lines available
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Original: |
J:310893 Xiao D, et al., PDK1 is important lipid kinase for RANKL-induced osteoclast formation and function via the regulation of the Akt-GSK3beta-NFATc1 signaling cascade. J Cell Biochem. 2020 Nov;121(11):4542-4557 |
All: |
1 reference(s) |
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