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Gene Expression Data
Assay Details
Assay
Reference: J:289914 Brown RM 2nd, et al., Notch-mediated lateral induction is necessary to maintain vestibular prosensory identity during inner ear development. Dev Biol. 2020 Jun 1;462(1):74-84
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6761856
Gene symbol: Lmx1a
Gene name: LIM homeobox transcription factor 1 alpha
Antibody: Anti-Lmx1 (AB10533)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 6A WT: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: otocyst epithelium Present Regionally restricted 6A WT right Expressed in the non-sensory epithelium surrounding the Sox2+ vestibular prosensory domain in a complementary fashion.
Specimen 6A cKO: embryonic day 10.5; Rbpjtm1.1Hon/Rbpjtm1Hon, Tg(Pax2-cre)1Akg/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: otocyst epithelium Present 6A cKO right Spreading of non-sensory expression into regions normally expressing SOX2 was seen.
Specimen 6B WT: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: otocyst epithelium Present Regionally restricted 6B WT right Expressed in the non-sensory epithelium surrounding the Sox2+ vestibular prosensory domain in a complementary fashion.
Specimen 6B cKO: embryonic day 11.5; Rbpjtm1.1Hon/Rbpjtm1Hon, Tg(Pax2-cre)1Akg/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: otocyst epithelium Present 6B cKO right Spreading of non-sensory expression into regions normally expressing SOX2 was seen.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
MGI 6.23 		The Jackson Laboratory