Casp3 Western blot Gene Expression Assay - GXD

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Gene Expression Data
Assay Details

Assay

Reference:	J:265712 Dziedzic SA, et al., ABIN-1 regulates RIPK1 activation by linking Met1 ubiquitylation with Lys63 deubiquitylation in TNF-RSC. Nat Cell Biol. 2018 Jan;20(1):58-68
Assay type:	Western blot
MGI Accession ID:	MGI:6761340
Gene symbol:	Casp3
Gene name:	caspase 3

Antibody:	anti-cleaved Caspase-3 (Asp175) (#9661)
Detection system:	Secondary antibody coupled to horseradish peroxidase
Assay notes:	Tissues were harvested in NP-40 lysis buffer.

Results

Image: 7b upper cleaved C3

	Sample Information		Bands	Other Sample Information
Lane	Age	Structure	20 kDa (a)	Genetic Background	Mutant Allele(s)	Sex
Abin+/+	E16.5	TS24: limb TS24: tail TS24: trunk	Ambiguous	involves: C57BL/6J		Not Specified
Abin-/- 1	E16.5	TS24: limb TS24: tail TS24: trunk	Present	involves: C57BL/6J	Tnip1^tm1.1Ama/Tnip1^tm1.1Ama	Not Specified
Abin-/- 2	E16.5	TS24: limb TS24: tail TS24: trunk	Present	involves: C57BL/6J	Tnip1^tm1.1Ama/Tnip1^tm1.1Ama	Not Specified
Abin-/- Ripk3-/-	E16.5	TS24: limb TS24: tail TS24: trunk	Ambiguous	involves: C57BL/6J * C57BL/6N	Ripk3^tm1Vmd/Ripk3^tm1Vmd, Tnip1^tm1.1Ama/Tnip1^tm1.1Ama	Not Specified
Abin-/- Ripk1D138N	E16.5	TS24: limb TS24: tail TS24: trunk	Ambiguous	involves: C57BL/6 * C57BL/6J	Ripk1^tm1.1Mkel/Ripk1^tm1.1Mkel, Tnip1^tm1.1Ama/Tnip1^tm1.1Ama	Not Specified

Notes:
(a) Cleaved form.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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