Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Leprem1(cre/ERT2)Smoc
Name:	leptin receptor; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
MGI ID:	MGI:6758026
Synonyms:	Lepr-2A-CreERT2, Leprem1(2A-CreERT2-Wpre-PA)Smoc
Gene:	Lepr  Location: Chr4:101574601-101672549 bp, + strand  Genetic Position: Chr4, 46.96 cM
Alliance:	Leprem1(cre/ERT2)Smoc page

Strain of Origin:

C57BL/6J

Allele Type:    Endonuclease-mediated (Inducible, Recombinase) Inducer:    tamoxifen Mutation:    Insertion   Leprem1(cre/ERT2)Smoc expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Lepr (MGI:104993)   Mutation details: 2A-CreERT2-Wpre-PA expression cassette was knocked into the Lepr gene stop codon site via CRISPR/Cas mediated recombination. (J:238766)

Activity:	Tissue activity of this recombinase allele
Driver:	Lepr (mouse) Summary of all recombinase alleles driven by Lepr. Alliance mouse Lepr gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lepr Mutation:	121 strains or lines available

Original:	J:238766 Shanghai Model Organisms Center, Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China. MGI Direct Data Submission. 2017;
All:	1 reference(s)