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Gene Expression Data
Assay Details
Assay
Reference: J:278529 Ma M, et al., Dynamic expression of N-myc in mouse embryonic development using an enhanced green fluorescent protein reporter gene in the N-myc locus. Dev Growth Differ. 2014 Feb;56(2):152-60
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6755526
Gene symbol: Mycn
Gene name: v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived
Reporter: GFP
Direct Detection
Results
Specimen 2A/a/a': embryonic day 15.5; Mycntm1.2Mlit/Mycn+ (more )
Structure Level Pattern Image Note
TS23: lens Present 2a' , 2A , 2a
TS23: retina Present 2A , 2a
Specimen 2B/b/b': embryonic day 15.5; Mycntm1.2Mlit/Mycn+ (more )
Structure Level Pattern Image Note
TS23: bronchiole epithelium Present 2B , 2b' , 2b Expressed in the epithelial cells in the distal lung buds.
Specimen 2g/g": embryonic day 13.5; Mycntm1.2Mlit/Mycn+ (more )
Note: Double labeled: green - Mycn; red - Mycn (assay MGI:6755533).
Structure Level Pattern Image Note
TS21: heart Present 2g , 2g" EGFP and anti-N-myc antibody fluorescence were localized at the same cells.
Specimen 3A: embryonic day 9.5; Mycntm1.2Mlit/Mycn+ (more )
Structure Level Pattern Image Note
TS15: 1st branchial arch Strong 3A Strongest expression.
TS15: 2nd branchial arch Strong 3A Strongest expression.
TS15: forelimb bud Strong 3A Strongest expression.
TS15: somite Strong Regionally restricted 3A Expression was strong in the 11th to 23rd.
TS15: eye Weak 3A
TS15: future brain Weak 3A
TS15: embryo Present Ubiquitous 3A
Specimen 3B: embryonic day 11.5; Mycntm1.2Mlit/Mycn+ (more )
Structure Level Pattern Image Note
TS19: 1st branchial arch Strong 3B Strongest expression.
TS19: 2nd branchial arch Strong 3B Strongest expression.
TS19: forelimb bud Strong 3B Strongest expression.
TS19: midbrain Weak 3B
TS19: trigeminal ganglion Strong 3B ganglion Gasseri
TS19: hindbrain Strong Regionally restricted 3B rhombencephalon with the fourth ventricle
TS19: anterior cardinal vein Strong 3B vena cardinalis anterior
TS19: embryo Present Ubiquitous 3B
TS19: ear Strong 3B
TS19: hindlimb bud Strong 3B
TS19: lens vesicle Strong 3B
TS19: tail Strong 3B
Specimen 3C: embryonic day 13.5; Mycntm1.2Mlit/Mycn+ (more )
Structure Level Pattern Image Note
TS21: hair follicle Strong 3C
TS21: lens Strong 3C
TS21: telencephalon Strong 3C
TS21: ear Present 3C
TS21: limb Present 3C Decreased expression.
TS21: embryo Present Ubiquitous 3C Highest expression.
Specimen 3D: embryonic day 15.5; Mycntm1.2Mlit/Mycn+ (more )
Structure Level Pattern Image Note
TS23: eye Weak 3D
TS23: telencephalon Weak 3D
TS23: hair follicle Strong 3D
Specimen 3E: embryonic day 17.5; Mycntm1.2Mlit/Mycn+ (more )
Structure Level Pattern Image Note
TS25: eye Weak 3E
TS25: telencephalon Weak 3E
Specimen 4A/A': embryonic day 13.5; Mycntm1.2Mlit/Mycn+ (more )
Structure Level Pattern Image Note
TS21: telencephalon Present Ubiquitous 4A , 4A' Including the colliculus ganglionaris and ventriculus lateralis.
TS21: lateral ventricle Present 4A , 4A'
Specimen 4B/B': embryonic day 13.5; Mycntm1.2Mlit/Mycn+ (more )
Structure Level Pattern Image Note
TS21: cerebellum Present Regionally restricted 4B , 4B' Expressed in the peripheral cells.
TS21: midbrain Present 4B , 4B' Including the corner.
Specimen 4C/C': embryonic day 13.5; Mycntm1.2Mlit/Mycn+ (more )
Structure Level Pattern Image Note
TS21: trigeminal ganglion Present 4C' , 4C ganglion Gasseri
Specimen 4D/D': embryonic day 13.5; Mycntm1.2Mlit/Mycn+ (more )
Structure Level Pattern Image Note
TS21: dorsal root ganglion Present 4D , 4D' Including the nerve plexus.
Specimen 4E/E': embryonic day 13.5; Mycntm1.2Mlit/Mycn+ (more )
Structure Level Pattern Image Note
TS21: lens Present 4E' , 4E
TS21: retina Present 4E' , 4E
Specimen 5A/a/a': embryonic day 13.5; Mycntm1.2Mlit/Mycn+ (more )
Structure Level Pattern Image Note
TS21: lens epithelium Strong Regionally restricted 5A , 5a' , 5a Expressed in the epithelium of the outer pole.
TS21: lens fiber Strong 5a , 5a' , 5A
TS21: retina Present 5A , 5a , 5a' Relatively weak.
Specimen 5B/b/b': embryonic day 15.5; Mycntm1.2Mlit/Mycn+ (more )
Structure Level Pattern Image Note
TS23: lens fiber Strong 5B , 5b , 5b'
TS23: retina Present 5B , 5b' , 5b Relatively weak.
TS23: retina layer Strong Regionally restricted 5B , 5b Expressed in the postmitotic ganglion cell layer.
Specimen 5C/c/c': embryonic day 17.5; Mycntm1.2Mlit/Mycn+ (more )
Structure Level Pattern Image Note
TS25: lens fiber Present Regionally restricted 5c , 5C , 5c' Expressed in the peripheral of lens, a region of differentiating lens fibers.
Specimen 6A/A': embryonic day 13.5; Mycntm1.2Mlit/Mycn+ (more )
Structure Level Pattern Image Note
TS21: visceral pericardium Present 6A , 6A' Higher expression.
TS21: cardiac muscle tissue Present 6A' , 6A
Specimen 6B/B': embryonic day 13.5; Mycntm1.2Mlit/Mycn+ (more )
Structure Level Pattern Image Note
TS21: liver Present Clusters 6B' , 6B Expressed in clusters near the portal vein.
Specimen 6C/C': embryonic day 13.5; Mycntm1.2Mlit/Mycn+ (more )
Structure Level Pattern Image Note
TS21: lobar bronchus epithelium Strong 6C' , 6C
TS21: lung mesenchyme Trace 6C , 6C'
Specimen 6D/D': embryonic day 13.5; Mycntm1.2Mlit/Mycn+ (more )
Structure Level Pattern Image Note
TS21: gut epithelium Present 6D' , 6D
TS21: gut muscularis Present 6D' , 6D
TS21: gut mesenchyme Weak 6D' , 6D
Specimen 6E/E': embryonic day 13.5; Mycntm1.2Mlit/Mycn+ (more )
Structure Level Pattern Image Note
TS21: mesonephric glomerulus Present 6E' , 6E
TS21: nephron Present 6E' , 6E
Specimen 6F/F': embryonic day 13.5; Mycntm1.2Mlit/Mycn+ (more )
Structure Level Pattern Image Note
TS21: adrenal gland Present Regionally restricted 6F , 6F' Expressed in the medullary, but not in the cortex.
Specimen not shown: postnatal; Mycntm1.2Mlit/Mycn+ (more )
Structure Level Pattern Image Note
TS28: eye Strong
Specimen not shown: embryonic day 9.5; Mycntm1.2Mlit/Mycn+ (more )
Structure Level Pattern Image Note
TS15: heart Strong
TS15: hepatic primordium Present Uniform
Specimen not shown: embryonic day 14.5; Mycntm1.2Mlit/Mycn+ (more )
Structure Level Pattern Image Note
TS22: heart Weak Expression declined sharply.
Specimen not shown: embryonic day 11.5; Mycntm1.2Mlit/Mycn+ (more )
Structure Level Pattern Image Note
TS19: liver Present Highest expression.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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