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Gene Expression Data
Assay Details
Assay
Reference: J:266234 Wylie LA, et al., Developmental SMAD6 loss leads to blood vessel hemorrhage and disrupted endothelial cell junctions. Dev Biol. 2018 Oct 15;442(2):199-209
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6753287
Gene symbol: Acta2
Gene name: actin alpha 2, smooth muscle, aorta
Results
Specimen 2V,V',V''': embryonic day 15.5; Smad6tm1Glvn/Smad6tm1Glvn (more )
Note: Multi-labeled: red - SMA (Acta2); green - Pecam1 (assay MGI:6753286); white - NG2 (Cspg4 assay MGI:6753288); blue - DAPI.; also light blue - Smad6 reporter (MGI:6753279).
Structure Level Pattern Image Note
TS23: aorta Present Regionally restricted 2V''' , 2V''' inset , 2V' , 2V , 2V inset Expression in smooth muscle. No overlap with Smad6 expression.
Specimen 2W,W',W''': postnatal day 3; Smad6tm1Glvn/Smad6tm1Glvn (more )
Note: Multi-labeled: red - SMA (Acta2); green - Pecam1 (assay MGI:6753286); white - NG2 (Cspg4 assay MGI:6753288); blue - DAPI.; also light blue - Smad6 reporter (MGI:6753279).
Structure Level Pattern Image Note
TS27: brain blood vessel Present Regionally restricted 2W''' inset , 2W , 2W''' , 2W' , 2W inset Expression in smooth muscle. No overlap with Smad6 expression.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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