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Gene Expression Data
Assay Details
Assay
Reference: J:293793 Basta JM, et al., The core SWI/SNF catalytic subunit Brg1 regulates nephron progenitor cell proliferation and differentiation. Dev Biol. 2020 Aug 15;464(2):176-187
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6740179
Gene symbol: Lef1
Gene name: lymphoid enhancer binding factor 1
Antibody: anti-Lef1 (#2230)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 5A Lef1 Brg1flx/flx: embryonic day 16.5; Smarca4tm1.2Pcn/Smarca4tm1.2Pcn (more )
Note: Triple labeled: green - Lef1; red - Ncam1 (assay MGI:6740176); blue - DAPI.
Structure Level Pattern Image Note
TS24: renal vesicle Present 5A Brg1flx/flx Lef1/NCAM
Specimen 5A Lef1 Six2Cre Brg1flx/flx: embryonic day 16.5; Smarca4tm1.2Pcn/Smarca4tm1.2Pcn, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: green - Lef1; red - Ncam1 (assay MGI:6740176); blue - DAPI.
Structure Level Pattern Image Note
TS24: renal vesicle Weak Regionally restricted 5A Six2Cre Brg1flx/flx Lef1/NCAM Authors report a 50% reduction in Lef1/NCAM+ differentiating structures.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/30/2024
MGI 6.23 		The Jackson Laboratory