About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:185870 Hazen VM, et al., BMP receptor-activated Smads confer diverse functions during the development of the dorsal spinal cord. Dev Biol. 2012 Jul 15;367(2):216-27
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6727114
Gene symbol: Lhx9
Gene name: LIM homeobox protein 9
Antibody: anti-LH2A/B
Detection system: Secondary antibody coupled to fluorescein
Assay notes: The specificity of the antibody used was not detailed; both family members have been annotated.
Results
Specimen 4A/C: embryonic day 10.5; Smad1tm1Abr/Smad1tm1Abr (more )
Note: Double labeled: green - Lhx2 and Lhx9; red - Isl1 (assay MGI:6727048).
Structure Level Pattern Image Note
TS17: neural tube lateral wall Present Regionally restricted 4C , 4A Expressed in commissural (dI1) neurons.
Specimen 4E/G: embryonic day 10.5; Smad1tm1Abr/Smad1tm1Abr, Tg(Pou3f4-cre)32Cren/0 (more )
Note: Conditional mutant. Double labeled: green - Lhx2 and Lhx9; red - Isl1 (assay MGI:6727048).
Structure Level Pattern Image Note
TS17: neural tube lateral wall Present Regionally restricted 4E , 4G Expressed in commissural (dI1) neurons, similar as in the control.
Specimen 4I/K: embryonic day 10.5; Smad5tm1Huy/Smad5tm1Huy (more )
Note: Double labeled: green - Lhx2 and Lhx9; red - Isl1 (assay MGI:6727048).
Structure Level Pattern Image Note
TS17: neural tube lateral wall Present Regionally restricted 4I , 4K Expressed in commissural (dI1) neurons.
Specimen 4M/O: embryonic day 10.5; Smad5tm1Huy/Smad5tm1Huy, Tg(Pou3f4-cre)32Cren/0 (more )
Note: Conditional mutant. Double labeled: green - Lhx2 and Lhx9; red - Isl1 (assay MGI:6727048).
Structure Level Pattern Image Note
TS17: neural tube lateral wall Present Regionally restricted 4O , 4M Reduced expression (>20%) in commissural (dI1) neurons, compared with the control.
Specimen not shown: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: neural tube lateral wall Present Regionally restricted Expressed in commissural (dI1) neurons.
Specimen not shown: embryonic day 10.5; Smad1tm1Abr/Smad1tm1Abr, Smad5tm1Huy/Smad5tm1Huy, Tg(Atoh1-cre)1Bfri/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: neural tube lateral wall Present Regionally restricted Reduced expression (30%) in commissural (dI1) neurons, compared with the control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory