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Gene Expression Data
Assay Details
Assay
Reference: J:177992 Nowell CS, et al., Foxn1 regulates lineage progression in cortical and medullary thymic epithelial cells but is dispensable for medullary sublineage divergence. PLoS Genet. 2011 Nov;7(11):e1002348
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6725803
Gene symbol: Plet1
Gene name: placenta expressed transcript 1
Antibody: MTS20
Assay notes: Two Plet1 antibodies were described, but the one used in this assay was not detailed. MTS24 MGI:6725779 may have been used in this assay.
Results
Specimen 4B R/- Plet-1: postnatal; Foxn1tm1.1Cbln/Foxn1tm1Tbo (more )
Note: Double labeled: red - Plet1; green - pan-cytokeratin.
Structure Level Pattern Image Note
TS28: thymus epithelium Present 4B R/- Plet-1 , 4B R/- merge
Specimen 4B -/- Plet-1: postnatal; Foxn1tm1Tbo/Foxn1tm1Tbo (more )
Note: Double labeled: red - Plet1; green - pan-cytokeratin.
Structure Level Pattern Image Note
TS28: thymus epithelium Strong 4B -/- Plet-1 , 4B -/- merge
Specimen 4C -4OHT Plet-1: postnatal; Foxn1tm1.1Cbln/Foxn1tm1Tbo, Gt(ROSA)26Sortm2(cre/ERT2)Brn/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Triple labeled: red - Plet1; green - pan-cytokeratin; blue - DAPI.
Structure Level Pattern Image Note
TS28: thymus epithelium Present 4C -4OHT Plet-1/PanK/DAPI , 4C -4OHT Plet-1
Specimen 5A -/- Plet-1: embryonic day 15.5; Foxn1tm1Tbo/Foxn1tm1Tbo (more )
Note: Double labeled: red - Plet1; green - K5 (Krt5 assay MGI:6725794).
Structure Level Pattern Image Note
TS23: thymus primordium Strong 5A -/- Plet-1/K5
Specimen 5A R/+ Plet-1: embryonic day 15.5; Foxn1tm1.1Cbln/Foxn1+ (more )
Note: Double labeled: red - Plet1; green - K5 (Krt5 assay MGI:6725794).
Structure Level Pattern Image Note
TS23: thymus primordium Ambiguous 5A R/+ Plet-1/K5
Specimen S5B E13.5 -/- Plet-1: embryonic day 13.5; Foxn1tm1Tbo/Foxn1tm1Tbo (more )
Note: Double labeled: red - Plet1; green - pan-cytokeratin.
Structure Level Pattern Image Note
TS21: thymus primordium Strong S5B E13.5 -/- Plet-1 , S5B E13.5 -/- merge High level expression maintained in thymus epithelial cells.
Specimen S5B E13.5 R/- Plet-1: embryonic day 13.5; Foxn1tm1.1Cbln/Foxn1tm1Tbo (more )
Note: Double labeled: red - Plet1; green - pan-cytokeratin.
Structure Level Pattern Image Note
TS21: thymus primordium Present S5B E13.5 R/- merge , S5B E13.5 R/- Plet-1
Specimen S5B E13.5 R/R Plet-1: embryonic day 13.5; Foxn1tm1.1Cbln/Foxn1tm1.1Cbln (more )
Note: Double labeled: red - Plet1; green - pan-cytokeratin.
Structure Level Pattern Image Note
TS21: thymus primordium Weak S5B E13.5 R/R merge , S5B E13.5 R/R Plet-1
Specimen S5B E13.5 R/+ Plet-1: embryonic day 13.5; Foxn1tm1.1Cbln/Foxn1+ (more )
Note: Double labeled: red - Plet1; green - pan-cytokeratin.
Structure Level Pattern Image Note
TS21: thymus primordium Present S5B E13.5 R/+ Plet-1 , S5B E13.5 R/+ merge
Specimen S5B E15.5 -/- Plet-1: embryonic day 15.5; Foxn1tm1Tbo/Foxn1tm1Tbo (more )
Note: Double labeled: red - Plet1; green - pan-cytokeratin.
Structure Level Pattern Image Note
TS23: thymus primordium Strong S5B E15.5 -/- merge , S5B E15.5 -/- Plet-1 High level expression maintained in thymus epithelial cells.
Specimen S5B E15.5 R/- Plet-1: embryonic day 15.5; Foxn1tm1.1Cbln/Foxn1tm1Tbo (more )
Note: Double labeled: red - Plet1; green - pan-cytokeratin.
Structure Level Pattern Image Note
TS23: thymus primordium Present S5B E15.5 R/- merge , S5B E15.5 R/- Plet-1
Specimen S5B E15.5 R/R Plet-1: embryonic day 15.5; Foxn1tm1.1Cbln/Foxn1tm1.1Cbln (more )
Note: Double labeled: red - Plet1; green - pan-cytokeratin.
Structure Level Pattern Image Note
TS23: thymus primordium Weak S5B E15.5 R/R Plet-1 , S5B E15.5 R/R merge
Specimen S5B E15.5 R/+ Plet-1: embryonic day 15.5; Foxn1tm1.1Cbln/Foxn1+ (more )
Note: Double labeled: red - Plet1; green - pan-cytokeratin.
Structure Level Pattern Image Note
TS23: thymus primordium Ambiguous S5B E15.5 R/+ Plet-1 , S5B E15.5 R/+ merge
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory