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Gene Expression Data
Assay Details
Assay
Reference: J:177992 Nowell CS, et al., Foxn1 regulates lineage progression in cortical and medullary thymic epithelial cells but is dispensable for medullary sublineage divergence. PLoS Genet. 2011 Nov;7(11):e1002348
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6725796
Gene symbol: Ly75
Gene name: lymphocyte antigen 75
Antibody: anti-CD205
Results
Specimen 3A CD205: postnatal week 6; Foxn1tm1.1Cbln/Foxn1tm1.1Cbln (more )
Note: Double labeled: green - CD205 (Ly75); red - pan-cytokeratin.
Structure Level Pattern Image Note
TS28: thymus epithelium Present Regionally restricted 3A CD205/panK , 3A CD205 Authors report overtly normal cortical and medullary compartments.

Specimen 5B -/- CD205: embryonic day 15.5; Foxn1tm1Tbo/Foxn1tm1Tbo (more )
Note: Double labeled: green - CD205 (Ly75); red - pan-cytokeratin.
Structure Level Pattern Image Note
TS23: thymus primordium Absent 5B -/- No expression detected at any stage.

Specimen 5B R/- CD205: embryonic day 15.5; Foxn1tm1.1Cbln/Foxn1tm1Tbo (more )
Note: Double labeled: green - CD205 (Ly75); red - pan-cytokeratin.
Structure Level Pattern Image Note
TS23: thymus primordium Present 5B R/-

Specimen 5B +/- CD205: embryonic day 15.5; Foxn1tm1Tbo/Foxn1+ (more )
Note: Double labeled: green - CD205 (Ly75); red - pan-cytokeratin.
Structure Level Pattern Image Note
TS23: thymus primordium Present 5B +/-


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory