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Gene Expression Data
Assay Details
Assay
Reference: J:202224 Crish J, et al., Keratin 5-Cre-driven excision of nonmuscle myosin IIA in early embryo trophectoderm leads to placenta defects and embryonic lethality. Dev Biol. 2013 Oct 1;382(1):136-48
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6725107
Gene symbol: Myh9
Gene name: myosin, heavy polypeptide 9, non-muscle
Antibody: anti-NMIIA
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 12A/B: embryonic day 12.5; Tg(KRT5-cre)5132Jlj/0, Myh9tm5Rsad/Myh9+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: yolk sac Present 12A , 12B Expressed in the cytoplasm and along the cortical regions of cells.
TS20: yolk sac blood vessel Strong Regionally restricted 12B , 12A Expressed in the endothelial cells.
Specimen 12C/D: embryonic day 12.5; Myh9tm5Rsad/Myh9tm5Rsad, Tg(KRT5-cre)5132Jlj/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: yolk sac Present 12D , 12C Significantly reduced expression along the cortical cell region of the yolk sac epithelium, compared with the control.
TS20: yolk sac blood vessel Strong 12D , 12C Expressed in the endothelial cells, similar as in the control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
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