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Gene Expression Data
Assay Details
Assay
Reference: J:290712 Ishiguro KI, et al., MEIOSIN Directs the Switch from Mitosis to Meiosis in Mammalian Germ Cells. Dev Cell. 2020 Feb 24;52(4):429-445.e10
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6721108
Gene symbol: Meikin
Gene name: meiotic kinetochore factor
Antibody: anti-Meikin
Detection system: Secondary antibody coupled to Alexa Fluor
Assay notes: Two Meikin antibodies were described, but the one used in this assay was not detailed. Anti-Meikin MGI:6720907 may have been used in this assay.
Results
Specimen 3E WT: postnatal week 8 (more )
Note: Triple labeled: red - Meikin; green - H3S10P; blue - DAPI.
Structure Level Pattern Image Note
TS28: seminiferous tubule Present 3E WT M , 3E WT
Specimen 3E Meiosin KO: postnatal week 8; Meiosinem1Keish/Meiosinem1Keish (more )
Note: Triple labeled: red - Meikin; green - H3S10P; blue - DAPI.
Structure Level Pattern Image Note
TS28: seminiferous tubule Absent 3E Meiosin KO M , 3E Meiosin KO Expression absent in prometaphase-like chromosomes.
Specimen 3E Stra8 KO: postnatal week 8; Stra8em4Keish/Stra8em4Keish (more )
Note: Triple labeled: red - Meikin; green - H3S10P; blue - DAPI.
Structure Level Pattern Image Note
TS28: seminiferous tubule Absent 3E Stra9 KO , 3E Stra9 KO M Expression absent in prometaphase-like chromosomes.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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