Gene Expression Data
Assay Details
Assay
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Reference:
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J:302708
Liu HB, et al., RNA-Binding Protein IGF2BP2/IMP2 is a Critical Maternal Activator in Early Zygotic Genome Activation. Adv Sci (Weinh). 2019 Aug 7;6(15):1900295
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:6720269
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Gene symbol:
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Igf2bp2
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Gene name:
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insulin-like growth factor 2 mRNA binding protein 2
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Results
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Specimen
1B GV:
postnatal
(more )
Note: Germinal vesicle stage oocyte.
Specimen
1B GV:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
postnatal
|
Sex:
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Female
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Type:
|
whole mount
|
Fixation:
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4% Paraformaldehyde
|
Note:
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Germinal vesicle stage oocyte.
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: primary oocyte |
Present |
|
1B GV top
,
1B GV bottom
|
Expression is in the cytoplasm.
|
Specimen
1B MII:
postnatal
(more )
Note: Metaphase II oocyte.
Specimen
1B MII:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
postnatal
|
Sex:
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Female
|
Type:
|
whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Note:
|
Metaphase II oocyte.
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: secondary oocyte |
Present |
|
1B MII top
,
1B MII bottom
|
Expression is in the cytoplasm.
|
Specimen
1B 1-cell:
embryonic day 0.5
(more )
Note: 1-cell stage embryo.
Specimen
1B 1-cell:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 0.5
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Age Note:
|
Age assigned by curator based on morphological criteria supplied by authors.
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Note:
|
1-cell stage embryo.
|
Specimen
1B 2-cell:
embryonic day 1.0
(more )
Note: 2-cell stage embryo.
Specimen
1B 2-cell:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 1.0
|
Age Note:
|
Age assigned by curator based on morphological criteria supplied by authors.
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Note:
|
2-cell stage embryo.
|
Specimen
1B 4-cell:
embryonic day 2.0
(more )
Note: 4-cell stage embryo.
Specimen
1B 4-cell:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 2.0
|
Age Note:
|
Age assigned by curator based on morphological criteria supplied by authors.
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Note:
|
4-cell stage embryo.
|
Specimen
1B 8-cell:
embryonic day 2.5
(more )
Note: 8-cell stage embryo.
Specimen
1B 8-cell:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 2.5
|
Age Note:
|
Age assigned by curator based on morphological criteria supplied by authors.
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Note:
|
8-cell stage embryo.
|
Specimen
1B Morula:
embryonic day 3.0
(more )
Note: Morula-cell stage embryo.
Specimen
1B Morula:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 3.0
|
Age Note:
|
Age assigned by curator based on morphological criteria supplied by authors.
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Note:
|
Morula-cell stage embryo.
|
Structure |
Level |
Pattern |
Image |
Note |
TS3: compacted morula |
Present |
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1B Morula bottom
,
1B Morula top
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Expression is in the cytoplasm with decreased accumulation at the outer edges of blastomeres.
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Specimen
1B Blast:
embryonic day 3.5
(more )
Note: Blastocyst-cell stage embryo.
Specimen
1B Blast:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 3.5
|
Age Note:
|
Age assigned by curator based on morphological criteria supplied by authors.
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Note:
|
Blastocyst-cell stage embryo.
|
Structure |
Level |
Pattern |
Image |
Note |
TS4: inner cell mass |
Present |
|
1B Blast bottom
,
1B Blast top
|
Expression is in the cytoplasm with decreased accumulation at the outer edges of blastomeres.
|
Specimen
S2A Control:
postnatal
(more )
Note: Metaphase II oocyte. Also stained with alpha-tubulin (red).
Specimen
S2A Control:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
postnatal
|
Sex:
|
Female
|
Type:
|
whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Note:
|
Metaphase II oocyte. Also stained with alpha-tubulin (red).
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: secondary oocyte |
Present |
|
S2A Control bottom
,
S2A Conrol top
,
S2A Control middle
|
|
Specimen
S2A Imp2-/-:
(close )
Genetic Background:
|
involves: C57BL/6 * ICR
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Mutant Allele(s):
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Igf2bp2tm1.1Hyfn/Igf2bp2tm1.1Hyfn
|
Age:
|
postnatal
|
Sex:
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Female
|
Type:
|
whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Note:
|
Metaphase II oocyte. Also stained with alpha-tubulin (red).
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: secondary oocyte |
Absent |
|
S2A Imp2-/- bottom
,
S2A Imp2-/- middle
,
S2A Imp2-/- top
|
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