Igf2bp2^tm1.1Hyfn
Targeted Allele Detail

Summary

• Symbol: Igf2bp2^tm1.1Hyfn
• Name: insulin-like growth factor 2 mRNA binding protein 2; targeted mutation 1.1, Heng-Yu Fan
• MGI ID: MGI:6509591
• Gene: Igf2bp2 Location: Chr16:21877759-21982049 bp, - strand Genetic Position: Chr16, 13.02 cM
• Alliance: Igf2bp2^tm1.1Hyfn page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:302708
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Exons 3 and 4 were deleted after Cre-mediated recombination of flanking loxP sites. (J:302708)

Expression

In Mice Carrying this Mutation:

33 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Igf2bp2 Mutation: 89 strains or lines available

References

• Original: J:302708 Liu HB, et al., RNA-Binding Protein IGF2BP2/IMP2 is a Critical Maternal Activator in Early Zygotic Genome Activation. Adv Sci (Weinh). 2019 Aug 7;6(15):1900295
• All: 1 reference(s)