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Gene Expression Data
Assay Details
Assay
Reference: J:306364 Lindholm P, et al., Novel neurotrophic factor CDNF protects and rescues midbrain dopamine neurons in vivo. Nature. 2007 Jul 5;448(7149):73-7
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6719235
Gene symbol: Cdnf
Gene name: cerebral dopamine neurotrophic factor
Antibody: anti-CDNF
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 2f: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cortical layer III Present 2f Authors report expression through layers II to VI.
Specimen 2j: postnatal adult (more )
Structure Level Pattern Image Note
TS28: CA3 pyramidal cell layer Present 2j Expression in CA1 to CA3 pyramidal region
Specimen not shown: postnatal adult (more )
Structure Level Pattern Image Note
TS28: dentate gyrus granule cell layer Present
TS28: dentate gyrus polymorphic layer Present
TS28: corpus striatum Weak
Specimen 2k: postnatal adult (more )
Structure Level Pattern Image Note
TS28: substantia nigra Present Single cells 2k Expression in solitary cells.
Specimen 2m: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Strong 2m
Specimen 2n: postnatal adult (more )
Structure Level Pattern Image Note
TS28: locus coeruleus Present 2n Expression in regions of brain stem, including locus coeruleus.
Specimen S5a: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: hippocampus CA3 Strong S5a High level of expression in hippocampus, especially CA3 region.
Specimen S5b: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: thalamus Present S5b
Specimen S5c: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: caudate-putamen Weak S5c Low levels of expression in caudate putamen (dorsal striatum).
Specimen S5d: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: substantia nigra Weak S5d Low levels of expression in substantia nigra.
Specimen S5e: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: hippocampus CA3 Present S5e
Specimen S5f: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: thalamus Present S5f
Specimen S5g: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: caudate-putamen Trace S5g Very weak expression.
Specimen S5h: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: substantia nigra Present S5h
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory