Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Igs2em8(KRT14-icre)Gpt
Name:	intergenic site 2; endonuclease-mediated mutation 8, GemPharmatech Co., Ltd
MGI ID:	MGI:6718926
Synonyms:	H11em1Cin(hKRT14-iCre), H11-hKRT14-iCre, keratin14-Cre
Gene:	Igs2  Location: unknown  Genetic Position: Chr11, Syntenic
Alliance:	Igs2em8(KRT14-icre)Gpt page

Strain of Origin:

C57BL/6JGpt

Allele Type:    Endonuclease-mediated (Recombinase) Mutation:    Insertion   Igs2em8(KRT14-icre)Gpt expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Homolog in Mouse Note human KRT14 (3861) Krt14  (MGI:96688)   Mutation details: CRISPR-targeting introduced an icre driven by human KRT14 enhancer and promoter into Igs2 H11 docking site. (J:293217)

Activity:	Tissue activity of this recombinase allele
Driver:	KRT14 (human) Summary of all recombinase alleles driven by KRT14. Alliance human KRT14 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Igs2 Mutation:	68 strains or lines available

Original:	J:306959 Qu H, et al., Dedicator of Cytokinesis 5 Regulates Keratinocyte Function and Promotes Diabetic Wound Healing. Diabetes. 2021 May;70(5):1170-1184
All:	2 reference(s)