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Gene Expression Data
Assay Details
Assay
Reference: J:266577 Rodrigo Albors A, et al., Lineage tracing of axial progenitors using Nkx1-2CreER(T2) mice defines their trunk and tail contributions. Development. 2018 Oct 2;145(19):dev164319
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6718555
Gene symbol: Nkx1-2
Gene name: NK1 homeobox 2
Reporter: Cre
Probe: Cre/ERT2 probe2
Probe preparation: Antisense RNA
Results
Specimen S3A: embryonic day 7.5; Nkx1-2tm2296.1(cre/ERT2)Arte/Nkx1-2+ (more )
Note: late-streak stage embryo (lateral view)
Structure Level Pattern Image Note
TS10: embryo Absent S3A
Specimen S3B: embryonic day 7.5; Nkx1-2tm2296.1(cre/ERT2)Arte/Nkx1-2+ (more )
Note: late-streak/early allantoic bud stage embryo (lateral view)
Structure Level Pattern Image Note
TS10: embryo Present Regionally restricted S3B Expression is seen in the caudal lateral epiblast.
Specimen S3C: embryonic day 7.5; Nkx1-2tm2296.1(cre/ERT2)Arte/Nkx1-2+ (more )
Note: early/late headfold stage embryo (lateral view)
Structure Level Pattern Image Note
TS11: primitive streak Present S3C Expression is seen in and alongside the primitive streak, in cells of the caudal lateral epiblast.
TS11: embryo Present Regionally restricted S3C Expression is seen in and alongside the primitive streak, in cells of the caudal lateral epiblast.
TS11: node Present S3C
Specimen S3Ca: embryonic day 7.5; Nkx1-2tm2296.1(cre/ERT2)Arte/Nkx1-2+ (more )
Note: early/late headfold stage embryo (transverse section)
Structure Level Pattern Image Note
TS11: primitive streak Present S3Ca Expression is seen in and alongside the primitive streak, in cells of the caudal lateral epiblast.
TS11: embryo Present Regionally restricted S3Ca Expression is seen in and alongside the primitive streak, in cells of the caudal lateral epiblast.
TS11: endoderm Ambiguous Single cells S3Ca Expression might be expressed in a few cells in the posterior endoderm.
Specimen S3Cb: embryonic day 7.5; Nkx1-2tm2296.1(cre/ERT2)Arte/Nkx1-2+ (more )
Note: early/late headfold stage embryo (transverse section)
Structure Level Pattern Image Note
TS11: primitive streak Present S3Cb Expression is seen in and alongside the primitive streak, in cells of the caudal lateral epiblast.
TS11: embryo Present Regionally restricted S3Cb Expression is seen in and alongside the primitive streak, in cells of the caudal lateral epiblast.
Specimen S3Cc: embryonic day 7.5; Nkx1-2tm2296.1(cre/ERT2)Arte/Nkx1-2+ (more )
Note: early/late headfold stage embryo (transverse section)
Structure Level Pattern Image Note
TS11: primitive streak Present S3Cc Expression is seen in the posterior of the embryo.
TS11: embryo Present Regionally restricted S3Cc Expression is seen in and alongside the primitive streak, in cells of the caudal lateral epiblast.
Specimen S3D: embryonic day 8.5; Nkx1-2tm2296.1(cre/ERT2)Arte/Nkx1-2+ (more )
Note: dorsal view
Structure Level Pattern Image Note
TS13: neural plate Present S3D
TS13: primitive streak Present S3D
TS13: embryo Present Regionally restricted S3D Expression is highest in epiblast cells in the node region and in the caudal lateral epiblast cells just posterior to the node.
Specimen S3Da: embryonic day 8.5; Nkx1-2tm2296.1(cre/ERT2)Arte/Nkx1-2+ (more )
Note: transverse section
Structure Level Pattern Image Note
TS13: neural plate Present S3Da
TS13: notochord Absent S3Da
Specimen S3Db: embryonic day 8.5; Nkx1-2tm2296.1(cre/ERT2)Arte/Nkx1-2+ (more )
Note: transverse section
Structure Level Pattern Image Note
TS13: neural plate Present S3Db
Specimen S3Dc: embryonic day 8.5; Nkx1-2tm2296.1(cre/ERT2)Arte/Nkx1-2+ (more )
Note: transverse section
Structure Level Pattern Image Note
TS13: primitive streak Present S3Dc
TS13: embryo Present Regionally restricted S3Dc Expression is seen in the caudal lateral epiblast cells just posterior to the node.
Specimen S3Dd: embryonic day 8.5; Nkx1-2tm2296.1(cre/ERT2)Arte/Nkx1-2+ (more )
Note: transverse section
Structure Level Pattern Image Note
TS13: embryo Absent S3Dd No expression is seen in the posterior-most section.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
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