Gene Expression Data
Assay Details
|
Assay
|
|
Reference:
|
J:272319
Tiveron MC, et al., Expression and function of CXCR7 in the mouse forebrain. J Neuroimmunol. 2010;224(1-2):72-9
|
|
Assay type:
|
RNA in situ
|
|
MGI Accession ID:
|
MGI:6715238
|
|
Gene symbol:
|
Cxcr4
|
|
Gene name:
|
C-X-C motif chemokine receptor 4
|
|
|
Results
|
Specimen
3C:
embryonic day 15.5
(more  )
Note: Double labeled: red - Cxcr4; green - Ackr3 (assay MGI:6715221).
Specimen
3C:
(close  )
|
Genetic Background:
|
CD-1
|
|
Age:
|
embryonic day 15.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Note:
|
Double labeled: red - Cxcr4; green - Ackr3 (assay MGI:6715221).
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS23: cerebral cortex intermediate zone |
Present |
Regionally restricted |
3C
|
The majority of interneurons in the subventricular zone/intermediate zone expressed both Ackr3 and Cxcr4 (57.7%), and 20.4% expressed only Cxcr4.
|
| TS23: cerebral cortex subventricular zone |
Present |
Regionally restricted |
3C
|
The majority of interneurons in the subventricular zone/intermediate zone expressed both Ackr3 and Cxcr4 (57.7%), and 20.4% expressed only Cxcr4.
|
Specimen
not shown:
embryonic day 15.5
(more )
Note: Also stained for Ackr3 (assay MGI:6715221).
Specimen
not shown:
(close )
|
Genetic Background:
|
CD-1
|
|
Age:
|
embryonic day 15.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Note:
|
Also stained for Ackr3 (assay MGI:6715221).
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS23: cerebral cortex marginal layer |
Present |
Regionally restricted |
|
More than 75% of all interneurons co-expressed Ackr3 and Cxcr4, and 6.8% expressed Cxcr4 alone in the marginal zone.
|
| TS23: cortical plate |
Present |
Regionally restricted |
|
Many interneurons in the cortical plate expressed both Ackr3 and Cxcr4 (47.5%), and less than 10% expressed Cxcr4 alone (7.3%).
|
|
Analysis Tools