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Gene Expression Data
Assay Details
Assay
Reference: J:242197 Jakubiczka-Smorag J, et al., Mouse model for molybdenum cofactor deficiency type B recapitulates the phenotype observed in molybdenum cofactor deficient patients. Hum Genet. 2016 Jul;135(7):813-26
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6712710
Gene symbol: Mocs2
Gene name: molybdenum cofactor synthesis 2
Reporter: lacZ
Direct Detection
Results
Specimen 3a: postnatal adult; Mocs2tm1(KOMP)Vlcg/Mocs2+ (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Present 3a
TS28: dentate gyrus Present 3a
TS28: hippocampus CA1 Present 3a
TS28: pons Present 3a

Specimen 3b: postnatal adult; Mocs2tm1(KOMP)Vlcg/Mocs2+ (more )
Structure Level Pattern Image Note
TS28: hippocampus CA1 Present 3b Brain LacZ , 3b CA1 LacZ
TS28: dentate gyrus Present 3b DG LacZ , 3b Brain LacZ
TS28: cerebral cortex Present 3b Brain LacZ , 3b Cortex LacZ
TS28: pons Present 3b Brainstem LacZ , 3b Brain LacZ

Specimen S4: embryonic day 8.0; Mocs2tm1(KOMP)Vlcg/Mocs2tm1(KOMP)Vlcg (more )
Structure Level Pattern Image Note
TS12: neural tube Present S4
TS12: somite Present S4
TS12: embryo Present Regionally restricted S4 Expression was detected in the headfolds.

Specimen S5a: postnatal adult; Mocs2tm1(KOMP)Vlcg/Mocs2+ (more )
Structure Level Pattern Image Note
TS28: liver Strong S5a

Specimen S5b: postnatal adult; Mocs2tm1(KOMP)Vlcg/Mocs2+ (more )
Structure Level Pattern Image Note
TS28: limiting ridge of stomach Present S5b
TS28: stomach mucosa Present S5b
TS28: stomach smooth muscle Present Regionally restricted S5b Expression was in longitudinal smooth muscle.

Specimen S5c: postnatal adult; Mocs2tm1(KOMP)Vlcg/Mocs2+ (more )
Structure Level Pattern Image Note
TS28: collecting duct Present S5c
TS28: renal calyx Present S5c
TS28: renal pelvis Present S5c

Specimen S5d: postnatal adult; Mocs2tm1(KOMP)Vlcg/Mocs2+ (more )
Structure Level Pattern Image Note
TS28: spermatogonium Strong S5d Expression was detected in undifferentiated spermatogonia.

Specimen S5e: postnatal adult; Mocs2tm1(KOMP)Vlcg/Mocs2+ (more )
Structure Level Pattern Image Note
TS28: mesenchymal stroma of ovary Weak S5e
TS28: oocyte Strong S5e

Specimen S5f: postnatal adult; Mocs2tm1(KOMP)Vlcg/Mocs2+ (more )
Structure Level Pattern Image Note
TS28: hair follicle Present S5f


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory