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Gene Expression Data
Assay Details
Assay
Reference: J:295945 Kawamura N, et al., Rab7-Mediated Endocytosis Establishes Patterning of Wnt Activity through Inactivation of Dkk Antagonism. Cell Rep. 2020 Jun 9;31(10):107733
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6711978
Gene symbol: Snx1
Gene name: sorting nexin 1
Antibody: anti-SNX1
Detection system: Secondary antibody
Results
Specimen 5A WT: embryonic day 6.0 (more )
Note: Triple labeled: blue - Snx1; green - Dkk1 (assay MGI:6711971); red - Lamp2 (assay MGI:6711977).
Structure Level Pattern Image Note
TS8: epiblast Present 5A1-5 , 5A1-3 , 5A1-2 , 5A1-1 Intracellular expressed in early endosomes, coexpressed with Dkk1.
TS8: primitive endoderm Present 5A1-5 , 5A1-3 , 5A1-2 , 5A1-1 Intracellular expressed in early endosomes, coexpressed with Dkk1.
Specimen 5A -/-: embryonic day 6.0; Rab7tm1.2Ywd/Rab7tm1.2Ywd (more )
Note: Triple labeled: blue - Snx1; green - Dkk1 (assay MGI:6711971); red - Lamp2 (assay MGI:6711977).
Structure Level Pattern Image Note
TS8: primitive endoderm Present 5A2-2 , 5A2-5 , 5A2-1 , 5A2-3 Expressed broadly, reflecting trafficking defects in the endocytic pathway. Not coexpressed with Dkk1.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory