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Gene Expression Data
Assay Details
Assay
Reference: J:295945 Kawamura N, et al., Rab7-Mediated Endocytosis Establishes Patterning of Wnt Activity through Inactivation of Dkk Antagonism. Cell Rep. 2020 Jun 9;31(10):107733
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6711977
Gene symbol: Lamp2
Gene name: lysosomal-associated membrane protein 2
Antibody: GL2A7
Detection system: Secondary antibody
Results
Specimen 5A WT: embryonic day 6.0 (more )
Note: Triple labeled: red - Lamp2; green - Dkk1 (assay MGI:6711971); blue - Snx1 (assay MGI:6711978).
Structure Level Pattern Image Note
TS8: primitive endoderm Present Regionally restricted 5A1-1 , 5A1-3 , 5A1-2 , 5A1-6 Expressed in the apical vacuoles, coexpressed with Dkk1 in some.
Specimen 5A -/-: embryonic day 6.0; Rab7tm1.2Ywd/Rab7tm1.2Ywd (more )
Note: Triple labeled: red - Lamp2; green - Dkk1 (assay MGI:6711971); blue - Snx1 (assay MGI:6711978).
Structure Level Pattern Image Note
TS8: primitive endoderm Present 5A2-1 , 5A2-2 , 5A2-6 , 5A2-3 Expressed in the apical vacuoles, which were highly fragmented, did not contain Dkk1.
Specimen 5B lower: embryonic day 6.5 (more )
Note: Double labeled: red - Lamp2; green - Dkk1 (assay MGI:6711971).
Structure Level Pattern Image Note
TS9: primitive endoderm Present Regionally restricted 5B2-3 , 5B2-1 , 5B2-2 Expressed in the apical vacuoles, coexpressed with Dkk1 in some.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory