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Gene Expression Data
Assay Details
Assay
Reference: J:241850 Naiman N, et al., Repression of Interstitial Identity in Nephron Progenitor Cells by Pax2 Establishes the Nephron-Interstitium Boundary during Kidney Development. Dev Cell. 2017 May 22;41(4):349-365.e3
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6711841
Gene symbol: Itga8
Gene name: integrin alpha 8
Antibody: anti-Itga8 (#AF4076)
Detection system: Secondary antibody coupled to DyLight
Results
Specimen S3E: embryonic day 18.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Pax2tm1.1Akio/Pax2+, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: green - Itga8; red - Cre reporter; white - cytokeratin
Structure Level Pattern Image Note
TS26: cap mesenchyme Present S3E
TS26: collecting duct Present S3E
Specimen S3F: embryonic day 18.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Pax2tm1.1Akio/Pax2tm1.2Akio, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: green - Itga8; red - Cre reporter; white - cytokeratin
Structure Level Pattern Image Note
TS26: cap mesenchyme Absent S3F
TS26: collecting duct Present S3F
Specimen S3G: embryonic day 18.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Pax2tm1.1Akio/Pax2+, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: green - Itga8; red - Cre reporter; white - cytokeratin
Structure Level Pattern Image Note
TS26: collecting duct Present S3G
TS26: renal medullary interstitium Present S3G
Specimen S3H: embryonic day 18.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Pax2tm1.1Akio/Pax2tm1.2Akio, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: green - Itga8; red - Cre reporter; white - cytokeratin
Structure Level Pattern Image Note
TS26: collecting duct Present S3H
TS26: renal medullary interstitium Present S3H
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
MGI 6.23 		The Jackson Laboratory