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Gene Expression Data
Assay Details
Assay
Reference: J:241850 Naiman N, et al., Repression of Interstitial Identity in Nephron Progenitor Cells by Pax2 Establishes the Nephron-Interstitium Boundary during Kidney Development. Dev Cell. 2017 May 22;41(4):349-365.e3
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6711820
Gene symbol: Vim
Gene name: vimentin
Antibody: anti-Vim (#AB5733)
Detection system: Secondary antibody coupled to DyLight
Results
Specimen 2O: embryonic day 18.5; Pax2tm1.1Akio/Pax2+, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: green - Vim; red - Tnc (assay MGI:6711822); blue - Acta2 (assay MGI:6711821)
Structure Level Pattern Image Note
TS26: renal cortical interstitium Present 2O

Specimen 2P: embryonic day 18.5; Pax2tm1.1Akio/Pax2tm1.2Akio, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: green - Vim; red - Tnc (assay MGI:6711822); blue - Acta2 (assay MGI:6711821)
Structure Level Pattern Image Note
TS26: renal cortical interstitium Present 2P Renal interstitium development is largely normal in the mutants even without nephron formation.

Specimen 2O': embryonic day 18.5; Pax2tm1.1Akio/Pax2+, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: green - Vim; red - Tnc (assay MGI:6711822); blue - Acta2 (assay MGI:6711821)
Structure Level Pattern Image Note
TS26: inner medullary interstitium Present 2O'
TS26: outer medullary interstitium Present 2O'

Specimen 2P': embryonic day 18.5; Pax2tm1.1Akio/Pax2tm1.2Akio, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: green - Vim; red - Tnc (assay MGI:6711822); blue - Acta2 (assay MGI:6711821)
Structure Level Pattern Image Note
TS26: inner medullary interstitium Present 2P' Renal interstitium development is largely normal in the mutants even without nephron formation.
TS26: outer medullary interstitium Present 2P' Renal interstitium development is largely normal in the mutants even without nephron formation.

Specimen 2O'': embryonic day 18.5; Pax2tm1.1Akio/Pax2+, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: green - Vim; red - Tnc (assay MGI:6711822); blue - Acta2 (assay MGI:6711821)
Structure Level Pattern Image Note
TS26: inner medullary interstitium Present 2O''

Specimen 2P'': embryonic day 18.5; Pax2tm1.1Akio/Pax2tm1.2Akio, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: green - Vim; red - Tnc (assay MGI:6711822); blue - Acta2 (assay MGI:6711821)
Structure Level Pattern Image Note
TS26: inner medullary interstitium Present 2P'' Renal interstitium development is largely normal in the mutants even without nephron formation.

Specimen 4S: embryonic day 18.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Pax2tm1.1Akio/Pax2+, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: green - Vim; red - Cre reporter; white - cytokeratin
Structure Level Pattern Image Note
TS26: inner medullary interstitium Present 4S

Specimen 4T: embryonic day 18.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Pax2tm1.1Akio/Pax2tm1.2Akio, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: green - Vim; red - Cre reporter; white - cytokeratin
Structure Level Pattern Image Note
TS26: inner medullary interstitium Present 4T

Specimen S2K: embryonic day 18.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Pax2tm1.1Akio/Pax2+, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: green - Vim; red - Tnc (assay MGI:6711822); blue - Acta2 (assay MGI:6711821)
Structure Level Pattern Image Note
TS26: renal interstitium Present S2K

Specimen S2L: embryonic day 18.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Pax2tm1.1Akio/Pax2tm1.2Akio, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: green - Vim; red - Tnc (assay MGI:6711822); blue - Acta2 (assay MGI:6711821)
Structure Level Pattern Image Note
TS26: renal interstitium Present S2L

Specimen S3M: embryonic day 15.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Pax2tm1.1Akio/Pax2+, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: green - Vim; red - Cre reporter; white - cytokeratin
Structure Level Pattern Image Note
TS23: renal medullary interstitium Present S3M

Specimen S3N: embryonic day 15.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Pax2tm1.1Akio/Pax2+, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: green - Vim; red - Cre reporter; white - cytokeratin
Structure Level Pattern Image Note
TS23: renal medullary interstitium Present S3N There is ectopic expression in the mutant.


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/30/2025
MGI 6.24
The Jackson Laboratory