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Gene Expression Data
Assay Details
Assay
Reference: J:293298 Zhang M, et al., Cdc42 Deficiency Leads To Epidermal Barrier Dysfunction by Regulating Intercellular Junctions and Keratinization of Epidermal Cells during Mouse Skin Development. Theranostics. 2019;9(17):5065-5084
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6711488
Gene symbol: Dsp
Gene name: desmoplakin
Antibody: anti-Desmoplakin (25318-1-AP)
Detection system: Secondary antibody coupled to Alexa Fluor 546
Results
Specimen 5C WT E15.5: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: epidermis Present 5C upper left Expressed in the desmosome.
Specimen 5C KO E15.5: embryonic day 15.5; Cdc42tm1Brak/Cdc42tm1Brak, Tg(KRT14-cre)1Cgn/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: epidermis Present 5C lower left Decreased expression in the desmosome compared with the wild-type.
Specimen 5C WT E17.5: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: epidermis Present 5C upper middle Expressed in the desmosome.
Specimen 5C KO E17.5: embryonic day 17.5; Cdc42tm1Brak/Cdc42tm1Brak, Tg(KRT14-cre)1Cgn/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS25: epidermis Present 5C lower middle Decreased expression in the desmosome compared with the wild-type.
Specimen 5C WT P1: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: epidermis Present 5C upper right Expressed in the desmosome.
Specimen 5C KO P1: postnatal day 1; Cdc42tm1Brak/Cdc42tm1Brak, Tg(KRT14-cre)1Cgn/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: epidermis Present 5C lower right Decreased expression in the desmosome compared with the wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory