About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:293298 Zhang M, et al., Cdc42 Deficiency Leads To Epidermal Barrier Dysfunction by Regulating Intercellular Junctions and Keratinization of Epidermal Cells during Mouse Skin Development. Theranostics. 2019;9(17):5065-5084
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6711452
Gene symbol: Krt1
Gene name: keratin 1
Antibody: anti-K1
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen S5B WT E15.5: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: epidermis Present S5B1-1 Expressed in the differentiated cells.
Specimen S5B KO E15.5: embryonic day 15.5; Cdc42tm1Brak/Cdc42tm1Brak, Tg(KRT14-cre)1Cgn/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: epidermis Present S5B1-4 Expressed in the differentiated cells, similar as in the wild-type.
Specimen S5B WT E17.5: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: epidermis Present S5B1-2 Expressed in the differentiated cells.
Specimen S5B KO E17.5: embryonic day 17.5; Cdc42tm1Brak/Cdc42tm1Brak, Tg(KRT14-cre)1Cgn/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS25: epidermis Present S5B1-5 Expressed in the differentiated cells, similar as in the wild-type.
Specimen S5B WT P1: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: epidermis Present S5B1-3 Expressed in the differentiated cells.
Specimen S5B KO P1: postnatal day 1; Cdc42tm1Brak/Cdc42tm1Brak, Tg(KRT14-cre)1Cgn/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: epidermis Present S5B1-6 Expressed in the differentiated cells. Increased expression compared with the wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory