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Gene Expression Data
Assay Details
Assay
Reference: J:293298 Zhang M, et al., Cdc42 Deficiency Leads To Epidermal Barrier Dysfunction by Regulating Intercellular Junctions and Keratinization of Epidermal Cells during Mouse Skin Development. Theranostics. 2019;9(17):5065-5084
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6711399
Gene symbol: Sprr2d
Gene name: small proline-rich protein 2D
Antibody: SPRR2D Polyclonal antibody (23046-1-AP)
Detection system: Secondary antibody coupled to Alexa Fluor 546
Results
Specimen 7B WT E15.5: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: epidermis Present Regionally restricted 7B3-1 Expressed in the stratum corneum, stratum granulosum and stratum spinosum.
Specimen 7B KO E15.5: embryonic day 15.5; Cdc42tm1Brak/Cdc42tm1Brak, Tg(KRT14-cre)1Cgn/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: epidermis Present Widespread 7B4-1 Expressed in all layers.
Specimen 7B WT E17.5: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: epidermis Present Regionally restricted 7B3-2 Expressed in the stratum corneum and stratum granulosum.
Specimen 7B KO E17.5: embryonic day 17.5; Cdc42tm1Brak/Cdc42tm1Brak, Tg(KRT14-cre)1Cgn/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS25: epidermis Present Widespread 7B4-2 Expressed in all layers.
Specimen 7B WT P1: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: epidermis cornified layer Present 7B3-3
TS27: epidermis basal layer Absent 7B3-3
TS27: epidermis granular layer Absent 7B3-3
TS27: epidermis spinous layer Absent 7B3-3
Specimen 7B KO P1: postnatal day 1; Cdc42tm1Brak/Cdc42tm1Brak, Tg(KRT14-cre)1Cgn/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: epidermis basal layer Present 7B4-3
TS27: epidermis cornified layer Present 7B4-3
TS27: epidermis granular layer Present 7B4-3
TS27: epidermis spinous layer Present 7B4-3
Specimen not shown: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: epidermis Present Widespread Expressed in all layers.
Specimen not shown: embryonic day 14.5; Cdc42tm1Brak/Cdc42tm1Brak, Tg(KRT14-cre)1Cgn/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: epidermis Present Widespread Expressed in all layers.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory