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Gene Expression Data
Assay Details
Assay
Reference: J:140053 Xie Z, et al., Zinc finger protein ZBTB20 is a key repressor of alpha-fetoprotein gene transcription in liver. Proc Natl Acad Sci U S A. 2008 Aug 5;105(31):10859-64
Assay type: RT-PCR
MGI Accession ID: MGI:6710972
Gene symbol: Afp
Gene name: alpha fetoprotein
Probe: Afp-pU1, Afp-pV1
Probe preparation: labelled with SYBR green
Results
Image: 2B ©

 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified (a) Amount Genetic BackgroundMutant Allele(s)Sex Note
2B P1 control P1 TS27: liver Present Not Specified; total RNA involves: 129S4/SvJae * C57BL/6 * DBA Zbtb20tm1Wpjz/Zbtb20tm1WpjzNot Specified
2B P1 KO P1 TS27: liver Present (b) Not Specified; total RNA involves: 129S4/SvJae * C57BL/6 * DBA Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+, Zbtb20tm1Wpjz/Zbtb20tm1WpjzNot Specified Conditional mutant.
2B P14 control P14 TS28: liver Weak Not Specified; total RNA involves: 129S4/SvJae * C57BL/6 * DBA Zbtb20tm1Wpjz/Zbtb20tm1WpjzNot Specified
2B P14 KO P14 TS28: liver Present (c) Not Specified; total RNA involves: 129S4/SvJae * C57BL/6 * DBA Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+, Zbtb20tm1Wpjz/Zbtb20tm1WpjzNot Specified Conditional mutant.
2B P21 control P21 TS28: liver Weak Not Specified; total RNA involves: 129S4/SvJae * C57BL/6 * DBA Zbtb20tm1Wpjz/Zbtb20tm1WpjzNot Specified
2B P21 KO P21 TS28: liver Present (c) Not Specified; total RNA involves: 129S4/SvJae * C57BL/6 * DBA Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+, Zbtb20tm1Wpjz/Zbtb20tm1WpjzNot Specified Conditional mutant.
2B P28 control P28 TS28: liver Weak Not Specified; total RNA involves: 129S4/SvJae * C57BL/6 * DBA Zbtb20tm1Wpjz/Zbtb20tm1WpjzNot Specified
2B P28 KO P28 TS28: liver Present (c) Not Specified; total RNA involves: 129S4/SvJae * C57BL/6 * DBA Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+, Zbtb20tm1Wpjz/Zbtb20tm1WpjzNot Specified Conditional mutant.
Notes:
(a) Expression declined >10,000-fold to basal levels in control liver within four weeks after birth. Whereas, levels in knockout liver were comparable at birth but decreased <5-fold in the first four weeks of age, which was followed by the high and constitutive expression throughout adult life.
(b) Similar as in the controls.
(c) Much higher expression compared with the controls.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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