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Gene Expression Data
Assay Details
Assay
Reference: J:294646 Stupnikov MR, et al., Jagged and Delta-like ligands control distinct events during airway progenitor cell differentiation. Elife. 2019 Oct 21;8:e50487
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6695149
Gene symbol: Scgb3a2
Gene name: secretoglobin, family 3A, member 2
Antibody: Mouse UGRP1/SCGB3A2 Antibody
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 3B control: embryonic day 18.5 (more )
Note: Triple labeled: green - Scgb3a2; Cyan - Calca (assay MGI:6695177); red - Fut4 (assay MGI:6695148).
Structure Level Pattern Image Note
TS26: lobar bronchus epithelium Present 3B control Expressed in secretory precursors.
Specimen 3B Jag1 cnull: embryonic day 18.5; Jag1tm1Jlew/Jag1tm1Jlew, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant. Triple labeled: green - Scgb3a2; Cyan - Calca (assay MGI:6695177); red - Fut4 (assay MGI:6695148).
Structure Level Pattern Image Note
TS26: lobar bronchus epithelium Present 3B Jag1cKO Expressed in secretory precursors, similar as in the control.
Specimen 3B Jag2 cnull: embryonic day 18.5; Jag2tm2.1Grid/Jag2tm2.1Grid, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant. Triple labeled: green - Scgb3a2; Cyan - Calca (assay MGI:6695177); red - Fut4 (assay MGI:6695148).
Structure Level Pattern Image Note
TS26: lobar bronchus epithelium Present 3B Jag2cKO Expressed in secretory precursors, similar as in the control.
Specimen 3B Jag1/2 cnull: embryonic day 18.5; Jag1tm1Jlew/Jag1tm1Jlew, Jag2tm2.1Grid/Jag2tm2.1Grid, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant. Triple labeled: green - Scgb3a2; Cyan - Calca (assay MGI:6695177); red - Fut4 (assay MGI:6695148).
Structure Level Pattern Image Note
TS26: lobar bronchus epithelium Present Clusters 3B Jag1/2cKO Expressed only in secretory precursors tightly associated with the developing neuroepithelial bodies. Nearly absent expression outside the neuroepithelial bodies.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/16/2024
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